Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD127 ( IL-7R α ) The CD127 antigen is a 75-80 kDa type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7R α . It forms a heterodimer with the common γ chain CD132 (IL-2R γ ), which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21, to form the high affinity IL-7 receptor. CD127 is found on normal B cell precursors but not on mature B lymphocytes. It is also expressed by thymocytes, the majority of peripheral T lymphocytes, a subset of monocytes and a subset of CD34+ cells. CD127 is a useful marker for identifying memory and effector T cells. Its expression is down-modulated on Treg cells. The ligation of IL -7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.

Lysed normal whole blood sample.

Clone: R34.34

Isotype: IgG1 Mouse

The R34.34 antibody inhibits binding of IL-7 to CD127.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

B25366 IM1980U A64617 A64618 B42026 A71116 B12700

1 mL 2 mL 1 mL 1 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP

PE

PC5 PC7 APC

0.5 mL 0.5 mL 0.5 mL

APC-A700 APC-A750

CD133 CD133, also known as AC133 or PROML1, is a 5-transmembrane glycoprotein of 120kDa belonging to the prominin family. It is mainly expressed on primitive cell populations such as CD34 hematopoietic stem and progenitor cells, neural and endothelial stem cells. In association with CD309 (KDR or VEGFR-2), CD133 allows the specific detection of endothelial progenitor cells. CD133 function is unknown although a naturally occurring mutation is associated with degenerative disease in the retina of affected patients.

Y79 cell line

Clone: W6B3C1 Isotype: IgG1 Mouse The clone W6B3C1 was assigned to CD133 during the Seventh HLDA Workshop on Human Leukocyte Differentiation Antigens. Similarly to AC133/1 clone, it recognizes the epitope 1.

Form

Size

Format

Part#

Status

Line Quality Standard

APC

C15190

0.5 mL

Liquid

ASR

IOTest

GMP

NEW

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 84 US Clinical Diagnostics Catalog