Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD90 The human CD90 antigen (also known as Thy-1) is the smallest (18 kDa) member of the immunoglobulin gene superfamily (IgSF). It is a highly glycosylated molecule with a glycosyl- phosphatidylinositol (GPI) anchor consisting of a single IgSF variable domain. The CD90 molecule has a broad tissue distribution and is expressed in nervous tissue, connective tissue and various stromal cell lines. It characterizes a rare subset of human fetal bone marrow cells, that contains multipotent hematopoietic progenitor activity. This antigen is expressed on a subset of CD34 positive cells from human bone marrow, cord blood or fetal liver. It is also expressed on very small subsets of thymocytes and peripheral T-lymphocytes.

Jurkat cell line: IL-2 producing T lymphocyte cell line

Form Clone: F15-42-1-5

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

IM1839U IM1840U

2 mL 2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PE

Form Clone: Thy1/310

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

B30649 IM3703 B36121

0.5 mL

Liquid Liquid Liquid

ASR ASR ASR

IOTest IOTest IOTest

GMP GMP GMP

PC5

1 mL

APC-A750

0.5 mL

CD94 ( NKG2a ) CD94 is a type II transmembrane glycoprotein of 30 kDa, belonging to the Ca++-dependent (C- type) lectin family. Like NKG2A (or Kp43) on human natural killer (NK) cells, CD94 associates with one member of the NKG2 family to form disulphide-linked, NK cell receptor for MHC class I molecules, with a broader specificity than the human killer cell inhibitory (KIR) / activator (KAR) receptors of the Ig-superfamily. Ligation of CD94 either potently triggers or inhibits NK cell proliferation and cell-mediated cytotoxicity. Recent studies strongly indicate that the specificity of CD94/NKG2 receptors is for HLA-E, a non-classical MHC class I molecule. CD94/NKG2A and CD94/NKG2B heterodimers constitute inhibitory NK cell receptors, whereas the association of CD94 with NKG2C corresponds to an activating receptor. The expression of CD94 appears restricted to most NK cells and to a T lymphocyte subpopulation including a subset of γδ TCR+ T-cells and αβ TCR+ CD8+ CD56+ T-cells, mainly V α 2/V δ 2. Isotype: IgG2a Mouse Ligation of CD94 with the HP-3B1 monoclonal antibody inhibits IL-2-dependent proliferation of NK-cells, and induces apoptosis in a subset of IL-2-stimulated NK cells. Clone: HP-3B1

Lysed normal whole blood sample.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

B90465 B09980

0.5 mL 0.5 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

APC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 79 US Clinical Diagnostics Catalog