Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD38 The CD38 antigen is a 45 kDa single chain type II integral membrane glycoprotein, with the NH2-terminus inside the cytoplasm. CD38 is an enzyme with several activities such as NAD glycohydrolase, ADP ribosylcyclase and cyclic ADP ribose hydrolase. CD38 is expressed on activated T and B lymphocytes, NK cells, monocytes, plasma cells and medullary thymocytes. CD38 depends on the differentiation and activation of the cell. In the B cell lineage, CD38 is expressed in early stages of B-cell ontogeny, lost during maturation and re-expressed upon terminal differentiation to plasma cells. CD38 is expressed on thymocytes and at a high level on activated T cells. Most mature resting lymphocytes of both B and T lineages do not express the CD38 antigen. CD38 is widely used as a marker to study T and B lymphocyte activation.

Lysed normal whole blood sample.

Form Clone: T16

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

IM0775U IM1832U

2 mL 2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PE

Form Clone: LS198-4-3

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB PE

B09683 IM2371U 6604928 A99022 IM2651U A70205 A54189 A60792 B23489 A86049

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP

2 mL

RD1 ECD PC5

0.5 mL 0.5 mL

CYTO - STAT

IOTest IOTest IOTest IOTest IOTest IOTest IOTest

1 mL

PC5.5

0.5 mL 0.5 mL

PC7 APC

1 mL

APC-A700 APC-A750

0.5 mL 0.5 mL

CD39 The CD39 molecule, known as ectonucleoside triphosphate diphosphohydrolase-1 (ENTPD1), is a 70-100 kDa integral membrane glycoprotein with two transmembrane domains. It belongs to the family of the primary enzymes responsible for cell surface nucleotide hydrolysis, with ATPase and ADPase activity. CD39 antigen is expressed on activated lymphocytes, regulatory T cells, B cells, and dendritic cells. It is involved in control of the extracellular nucleoside triphosphate pool (NTP), suppression of inflammation and control of platelet activation. The coordinated expression of CD39/CD73 on Tregs and the adenosine A2A receptor on activated T effector cells generates immunosuppressive loops. In human studies, it has been reported that CD4+CD25-CD39+ T cells are T inducers.

Lysed normal whole blood sample.

Form Clone: BA54

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PE

B55384 B55385

1 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PC5.5

0.5 mL

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 59 US Clinical Diagnostics Catalog