Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD36 The CD36 antigen (platelet GPIV, or GPIIIb) is a generic term for a family of glycoproteins with molecular weights ranging from 78 to 88 kDa. CD36 expression occurs in different types of cells, including mammary epithelial cells, endothelial cells monocytes, macrophages, platelets, megakaryocytes and early erythroid cells. This molecule is also found on some human tumor cell lines. It is a very early marker of erythroid differentiation and mediates the adherence of platelets to thrombospondin and collagen. CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA). As a result of its multiple ligands and signal transduction capabilities, CD36 has also a number of functions related to immune responses, inflammation and blood disorders.

Lysed normal whole blood sample.

Clone: FA6.152 Isotype: IgG1 Mouse The FA6-152 monoclonal antibody, raised against fetal erythrocytes, recognizes the CD36 family of antigens on platelets and certain hematopoietic cells. It does not react with lymphocytes or granulocytes. It reacts with both fetal and adult monocytes, megakaryocytes, platelets, and with reticulocytes.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

B43302 IM0766U A87786 B46022

0.5 mL

Liquid Liquid Liquid Liquid

ASR ASR ASR ASR

IOTest IOTest IOTest IOTest

GMP GMP GMP GMP

FITC APC

2 mL

0.5 mL 0.5 mL

APC-A700

CD37 The CD37 antigen is a 40-52 kDa single chain transmembrane protein with 4 transmembrane domains (Tetraspan/TM4SF). It has both its NH2- and COOH-termini inside the cells, and is heavily glycosylated on one extracellular loop. Its main feature is its high content of hydrophobic residues (45%). CD37 is strongly expressed on the surface of human peripheral blood B lymphocytes and on B cells from germinal centers. In the ontogeny of B cells, this antigen appears late, after the pre-B stage, and is not expressed on plasma cells. CD37 has a low expression on T lymphocytes, granulocytes, and monocytes. It is weakly expressed by other cellular types such as Langerhans cells, macrophages, normal medullar granulous cells and peripheral blood polymorphonuclear cells. CD37 is involved in signal transduction.

Lysed normal whole blood sample.

Form Clone: BL14

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

IM0457 IM0458

2 mL 2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PE

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 58 US Clinical Diagnostics Catalog