Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD23 The CD23 antigen (also called B6) is a transmembrane glycoprotein with a molecular weight of 45 kDa, spatially associated with the major histocompatibility complex (MHC) Class II antigen. The CD23 molecule, also named Fc ε RII is the low affinity receptor for IgE. CD23 antigen is primarily expressed on B lymphocytes and monocytes. It is also present on a large variety of other cells such as T lymphocytes, eosinophils, platelets, Langerhans cells, follicular dendritic cells (FDC), a subset of thymic epithelial cells and neutrophils. On B lymphocytes, CD23 expression is up-regulated upon activation and ultimately lost upon differentiation towards secreting-plasmocytes. A soluble form of CD23 (sCD23) exists and may be involved (like CD23) in the regulation of IgE synthesis and inflammatory phenomenom.

Lysed normal whole blood sample.

Form Clone: HD50 (B6)

Isotype: IgG2b Mouse

Size

Format

Part#

Status

Line Quality Standard

RD1

6604426

0.5 mL

Liquid

ASR

GMP

CYTO - STAT

Clone: 9P25

Isotype: IgG1 Mouse

9P25 blocks the binding of IgE.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A93689 IM0529U A33099 IM3609U B12935 A69964 A70207

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP

FITC

2 mL 2 mL 1 mL

PE

ECD PC7 APC

0.5 mL

1 mL

APC-A700

0.5 mL

CD24 The CD24 antigen is a glycosyl-phosphatidylinositol-linked membrane sialoglycoprotein, with a molecular weight of 35-45 kDa. CD24 is present on B cells, from the pre-B to the mature B cell stage, but not on plasma cells. It is expressed on mature granulocytes and on a variety of epithelial cell types. CD24 was discovered in mice as a heat-stable antigen and was used as a marker to differentiate hematopoietic cells and neuronal cells. It is currently known that CD24 serves as a costimulatory factor of T cells that regulate their homeostasis and proliferation, while in B cells, CD24 is functionally involved in cell activation and differentiation. In hematopoietic cells, CD24 is known to bind to molecules exhibiting danger-associated molecular patterns (DAMPs). CD24 mediates signal transduction and activates the mitogen- activated protein kinase pathway, which involves B- and T-cell development and apoptosis, cell binding and granulocyte oxidative burst.

Lysed normal whole blood sample.

Form Clone: ALB9

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PE

IM1428U B12699 IM2645 B23133 A87785 B10738

2 mL

Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP

ECD PC5

0.5 mL

1 mL

PC5.5

0.5 mL 0.5 mL 0.5 mL

APC

APC-A750

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 51 US Clinical Diagnostics Catalog