Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD19 The CD19 antigen (also called B4) is a type I membrane glycoprotein with a molecular weight of 95 kDa. It is a signal transduction molecule that regulates lymphocyte development, activation, and differentiation. The molecule is expressed on all normal B lymphocytes including pro-B lymphocytes, but it is lost in maturation to plasma cells. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normal T lymphocytes, NK cells, monocytes, and granulocytes. CD19 can be associated with other surface molecules including CD21 and CD81. Co-ligation of the CD19-CD21-CD81 complex with the surface IgM-B-cell antigen receptor (BCR) leads to the phosphorylation of CD19 by Syk, followed by the recruitment of positive signal transduction effectors such as phosphatidylinositol 3 kinase (PI3 kinase), Lyn, and Fyn.

Lysed normal whole blood sample.

Form Clone: 89B (B4)

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

B36534 B36536

0.5 mL 0.5 mL

Liquid Liquid

ASR ASR

GMP GMP

CYTO - STAT CYTO - STAT

RD1

Clone: J3-119 Isotype: IgG1 Mouse In vitro studies show that the CD19 antibodies have an inhibitory effect on the activation and proliferation of B lymphocytes. They also inhibit the B cell response after co-stimulation by anti-immunoglobulin and interleukin 4.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A86355 A96418 IM1284U IM1285U IM2708U IM2643U A66328 IM3628U IM2470U B76283 A78837 A78838

0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP

KrO FITC

2 mL 2 mL 1 mL 1 mL

PE

ECD PC5

PC5.5

0.5 mL

PC7 APC

1 mL 1 mL

AF700

0.5 mL 0.5 mL 0.5 mL 0.2 mg

APC-A700 APC-A750

UNLB

IM1313

Freeze-dried

-

Form Clone: HD237 (B4 lytic)

Isotype: IgG2b Mouse

Size

Format

Part#

Status

Line Quality Standard

ECD

6604551

0.5 mL

Liquid

ASR

GMP

CYTO - STAT

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 48 US Clinical Diagnostics Catalog