Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD15 The CD15 antigen (Lewis x or Lex) is the lacto-N-(neo) fucopentaose III molecule. This carbohydrate epitope is carried by both glycolipids and glycoproteins expressed on the cell membrane. CD15 antigen is strongly expressed by neutrophils, eosinophils, monocytes, macrophages, mast cells and normal myeloid precursor cells. It is not expressed on normal erythrocytes, platelets or lymphocytes. CD15 may function as an important signaling molecule capable of initiating proinflammatory events in monocytes that come into contact with activated endothelium.

Lysed normal whole blood sample.

Form Clone: 80H5

Isotype: IgM Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

A74775 B01176 IM1423U IM1954U IM2641U

0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP

KrO FITC

2 mL 2 mL 1 mL

PE

PC5

CD16 The CD16 antigen is the low-affinity receptor for IgG (Fc γ RIII). The CD16 antigen exists in two different forms encoded by two different genes: Fc γ RIIIA (or III-2) and Fc γ RIIIB (or III-1). The genetic heterogeneity of CD16 generates alternative membrane-anchored molecules. One is a transmembrane form (Fc γ RIIIA, 50-65 kDa) expressed on NK cells, monocytes and macrophages. The other is a glycosylphosphatidylinositol (GPI)-anchored form (Fc γ RIIIB, 48 kDa) only expressed on neutrophils. It has been shown that the CD16 antigen can be non- covalently associated within the membrane of NK cells, to a disulfide-linked homo or heterodimer made from the 16 kDa CD3 ζ chain and the Fc ε RI γ chain.

Lysed normal whole blood sample.

Clone: 3G8 Isotype: IgG1 Mouse The 3G8 monoclonal antibody is inappropriate for western blot use. 3G8 binds to both isoforms of the CD16 molecule.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A82792 B00069 6604894 IM0814U IM1238U A33098 IM2642U B00845 B20023 A66330

0.5 mL 0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP

KrO FITC FITC ECD PC5 APC PE

CYTO - STAT

2 mL 2 mL 1 mL 1 mL

IOTest IOTest IOTest IOTest IOTest IOTest IOTest

0.5 mL 0.5 mL 0.5 mL 0.2 mg

APC-A700 APC-A750

UNLB

IM0813

Freeze-dried

-

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 46 US Clinical Diagnostics Catalog