Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD11c CD11c (integrin α X subunit, also known as leucocyte surface antigen p150, Axb2 and CR4) is a member of the integrin family. Like other leucocyte integrins (CD11a, CD11b, CD11d), CD11c is non-covalently associated with the β 2 integrin subunit (CD18). CD11c is a transmembrane glycoprotein of 145-150 kDa, mainly expressed by monocytes, macrophages and NK cells, and to a lesser extent by granulocytes, dendritic cells and some subsets of T and B cells. CD11c / CD18 has an important role in cytotoxic T cell killing, in the adhesion of monocytes and neutrophils to the endothelium and induces cellular activation. The CD11c is ∼ 87% homologous in sequence to CD11b, and recognizes similar ligands including complement factor fragment iC3b, fibrinogen, CD54 and bacterial lipopolysaccharide.

Lysed normal whole blood sample.

Clone: BU15

Isotype: IgG1 Mouse

The BU15 antibody was used as a CD11c reference mAb (ref.6) during HLDA 6.

Form

Size

Format

Part#

Status

Line Quality Standard

PE

IM1760U IM3707 B19719 A80249 B01680 B43304

2 mL 1 mL

Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP

PC5

PC5.5

0.5 mL

PC7 APC

1 mL

0.5 mL 0.5 mL

APC-A700

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 43 US Clinical Diagnostics Catalog