Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD8 The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8 α homodimer or as a CD8 α / β heterodimer. CD8 α is required for surface expression of CD8 β . The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain ( α 3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8 α homodimer is expressed by NK cells and γ / δ + T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes.

Lysed normal whole blood sample.

Clone: B9.11 Isotype: IgG1 Mouse The B9.11 monoclonal antibody recognizes the α chain of the CD8 molecule. It was used as a CD8 reference monoclonal antibody during HLDA 6 (ref. 6T-CD8.5).

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A82791 B00067 IM0451U IM0452U B08467 IM2638U IM2469U B76279 A66332 A94686 B21205

0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP

KrO FITC

2 mL 2 mL

PE

ECD PC5

0.5 mL

1 mL

PC5.5

0.5 mL

APC

1 mL

AF700

0.5 mL 0.5 mL 0.5 mL

APC-A700 APC-A750

Clone: SFCI21Thy2D3 (T8)

Isotype: IgG1 Mouse

Form SFCI21Thy2D3 monoclonal antibody recognizes the α chain of the CD8 molecule. Part# Format Size Status

Line Quality Standard

ECD PC5

6604728 6607011 A99019 A99023

0.5 mL 0.5 mL 0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid

ASR ASR ASR ASR

GMP GMP GMP GMP

CYTO - STAT CYTO - STAT

PC5.5

IOTest IOTest

APC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 39 US Clinical Diagnostics Catalog