Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD6 The CD6 antigen is a single-chain type I transmembrane glycoprotein with three extracellular SRCR domains. It exists predominantly in two isoforms as 100 kDa and 130 kDa. CD6 is an extensively glycosylated molecule and differences in glycosylation patterns may occur. The CD6 molecule is modified by phosphorylation of serine, threonine and tyrosine residues during T-cell activation. CD6 have a role as a costimulatory molecule for T-cell activation and in cell adhesion. CD166 was identified as an adhesion receptor for CD6. The CD6 antigen is expressed on the surface of most mature human T cells and a subset of resting B cells and medullary thymocytes. It is found on NK cells not it is reported to be on any other cells.

Lysed normal whole blood sample.

Form Clone: 2H46D3B

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

B16492

1 mL

Liquid

ASR

IOTest

GMP

CD7 The CD7 antigen is a membrane-embedded glycoprotein with a molecular weight of 40 kDa. It is expressed at an early stage of T lineage ontogeny, during the extrathymic prothymocytic formation. CD7 expression persists throughout T lymphocytes differentiation defining CD7 as a pan-T marker. It is also expressed on thymocytes, on the majority of resting T lymphocytes, and Natural Killer cells (NK), and on a subset of pre-B lymphocytes and B lymphocytes from foetal bone marrow. CD7 expression is also detected on pluripotent hematopoietic stem cells. Mature B-lymphocytes, cells from erythroid, myeloid and megacaryocytic lineage do not express the CD7 molecule. The CD7 molecule is involved in T lymphocytes activation. Its expression may be quantitatively up-regulated on stimulated T lymphocytes.

Lysed normal whole blood sample.

Clone: 3A1E-12H7

Isotype: IgG2b Mouse

3A1E-12H7 (ref. 6T-CD7.4) was used as a CD7 reference monoclonal antibody during HLDA 6.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC FITC

6603824 6603825 6603822 6603827

CYTO - STAT

0.5 mL 0.1 mg 0.5 mL 0.5 mL

Liquid

ASR ASR ASR ASR

GMP GMP GMP GMP

Freeze-dried

COULTER CLONE

RD1 RD1

CYTO - STAT

Liquid Liquid

COULTER CLONE

Form Clone: 8H8.1

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

B06499 IM0585U IM1429U A70202 IM3613U A46526 A97050 A70201

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP

FITC

2 mL 2 mL 1 mL 1 mL 1 mL

PE

ECD PC5 PC7 APC

0.5 mL 0.5 mL 0.5 mL

APC-A700 APC-A750

B16892

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 38 US Clinical Diagnostics Catalog