Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD5 CD5 is a type I transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of nearly 100 amino acids each. The CD5 is expressed at the surface of mature T lymphocytes, by most of thymocytes and by a subpopulation of B lymphocytes (B-1a) expanded in neonatal life, several autoimmune disorders and some B-cell proliferative disorders (B-CLL). It is not found on granulocytes, monocytes and platelets. The CD5 antigen is the ligand for the B-lymphocytes cell-surface protein CD72. The CD5 / CD72 interactions are involved in the regulation of T and B lymphocyte activation and proliferation. B lymphocytes can be divided into B-1 lymphocytes and B-2 (or conventional B) lymphocytes based on different localization, functional characteristics and gene expression. The B-1 lymphocyte subset is divided into B-1a and B-1b subpopulations, which do or do not express the CD5 antigen respectively. The B-1a CD5+ B lymphocyte subset expresses immunoglobulin with inherent low affinities for self-antigens.

Lysed normal whole blood sample.

Clone: BL1a

Isotype: IgG2a Mouse

BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA / 6.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A82790 IM0468U IM0469U A33096 IM2637U A70203 A51075 A60790 A78835 A78836

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP

FITC

2 mL 2 mL 1 mL 1 mL

PE

ECD PC5

PC5.5

0.5 mL

PC7 APC

1 mL 1 mL

APC-A700 APC-A750

0.5 mL 0.5 mL

Form Clone: CLB-T1/1

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

ECD APC

B55387 B55386

0.5 mL 0.5 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 37 US Clinical Diagnostics Catalog