Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD3 CD3 ζ see TCR ζ .

The CD3 antigen is a complex of 5 invariable polypeptidic chains: γ , δ , ε , ζ and η , whose molecular weights are respectively 25-28, 21, 20, 16 and 22 kDa. The CD3 chains are clustered in a group of two invariant dimers, γ / ε and δ / ε associated with a variable dimer which consists of ζ homodimers, or ζ / η , or ζ / γ FcR heterodimers ( γ FcR being the γ chain of the Fc receptors), or γ FcR homodimers. The CD3 is part of a bigger complex which includes the T Cell Receptor (TCR). CD3 complex associated with the TCR is involved in the recognition of peptides bound to the major histocompatibility complex class I and II during the immune response. T cell activation may be induced when a foreign antigen is presented to the TCR through MHC complex. The CD3 antigen is expressed by mature T lymphocytes and by a subset of thymocytes. Isotype: IgG1 Mouse UCHT1 reacts with the ε -chain of the CD3 complex. It was used as a CD3 reference mAb (ref.6T-CD3.1) during HLDA 6. After permeabilization with saponin-based permeabilization reagent IntraPrep, it may be used to detect intracytoplasmic CD3 by flow cytometry. Clone: UCHT1

Lysed normal whole blood sample.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A93687 B00068 IM1281U IM1282U IM2705U 6607010 IM2635U A66327 IM2467U B10823 A66329

0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP GMP

KrO FITC

2 mL 2 mL 1 mL

PE

ECD PC5 PC5

0.5 mL

CYTO - STAT

1 mL

PC5.5

0.5 mL

APC

1 mL

APC-A700 APC-A750

0.5 mL 0.5 mL

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 35 US Clinical Diagnostics Catalog