Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

CD1c The CD1c antigen (also called BDCA-1) is a member of the CD1 family of proteins that are structurally related to MHC class I proteins. CD1c is a membrane glycoprotein with a molecular weight of 43 kDa, non-covalently associated with β 2-microglobulin. CD1c antigen is expressed on a major subpopulation of human myeloid dendritic cells. In blood, CD1c is also expressed on a subpopulation of CD19+ small resting B lymphocytes. Its expression has also been detected on cortical thymocytes (weakly), on Langerhans cells and on dendritic cells. CD1c+ myeloid dendritic cells have been designated as type-1 myeloid dendritic cells (MDC1s). It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.

Lysed normal whole blood sample.

Form Clone: L161

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PC5.5

B46036

0.5 mL

Liquid

ASR

IOTest

GMP

CD2 The CD2 antigen (also called LFA-2 or T11 antigen) is a 50 kDa single chain type I transmembrane glycoprotein that comprises two external domains belonging to the immunoglobulin superfamily (IgSF). It was formerly described as the sheep red blood cell receptor, causing T-cell rosetting. Signaling molecules, such as Fyn, Lck and the PI3-kinase, have been reported to associate with the intracellular domain of CD2. CD2 has been identified as the ligand for CD58 (LFA-3). It is also a receptor for CD48, CD59 and CD15. The CD58-CD2 interaction is a component of intercellular adhesion and costimulatory signaling in T cells. CD2 is involved in the regulation of human T-cell cytokine production, and in a Fas-independent induced apoptosis of activated human peripheral T cells. CD2 is present on all human non-B peripheral lymphocytes, on the majority of thymic T cells, and on a subset of thymic B cells.

Lysed normal whole blood sample.

Clone: SFCI3Pt2H9 (T11) Isotype: IgG1 Mouse SFCI3Pt2H9 inhibits sheep erythrocyte rosette formation. It has been used as a CD2 reference monoclonal antibody during HLDA 6 (ref.6T-CD2.6).

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

B36533 629776

CYTO - STAT CYTO - STAT

0.5 mL 0.5 mL

Liquid Liquid

ASR ASR

GMP GMP

RD1

Clone: 39C1.5 Isotype: IgG2a Rat 39C1.5 inhibits sheep erythrocyte rosette formation. It has been used as a CD2 reference monoclonal antibody during HLDA 6 (ref 6T-CD2.7).

Form

Size

Format

Part#

Status

Line Quality Standard

PB

B09685 IM0442U IM0443U B46023 IM2634U A51074 A60794

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR ASR ASR ASR ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP GMP GMP GMP GMP GMP GMP

FITC

2 mL 2 mL

PE

ECD PC5 PC7 APC

0.5 mL

1 mL 1 mL 1 mL

APC-A700 APC-A750

B12111 B01681

0.5 mL 0.5 mL

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 34 US Clinical Diagnostics Catalog