Flow Cytometry catalog - US 2019

Single-Color Conjugated Antibodies

Analyte Specific Reagents - ASR product list

HLA-DR, DP, DQ The recognized epitope is specific to a non-polymorphic HLA class II (DR, DP, DQ) Ia antigen constituted of α and β polypeptides of 34 and 29 kDa respectively. This antigen is expressed on monocytes, macrophages, B lymphocytes and activated T lymphocytes.

Form Clone: 9-49 (I3)

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

6603424 6604366

0.5 mg 0.5 mL

Freeze-dried

ASR ASR

GMP GMP

COULTER CLONE

RD1

CYTO - STAT

Liquid

IFN- γ Human Interferon- γ (IFN- γ ) is a 20-25 kDa (monomer) pleiotrophic cytokine that is produced by activated T cells and NK cells and is involved in the regulation of almost all immune and inflammatory responses. IFN- γ is involved in the activation, growth and differentiation of T cells, B cells, macrophages, NK cells as well as other cell types. IFN- γ enhances MHC expression on antigen-presenting cells including epithelial, endothelial and connective tissue cell and monocytes cell lines. It also has weak antiviral activity and acts as a macrophage-activating factor (MAF) for tumor cytotoxicity leading to anti-tumor effects.

Activated peripheral blood lymphocytes (PBL).

Form Isotype: IgG1 Mouse The FITC- and PE-conjugated forms of the 45.15 antibody are optimized for flow cytometric detection of intracellular IFN- γ in stimulated peripheral blood mononuclear cells (PBMC) after permeabilization with IntraPrep permeabilization reagent. Part# Format Size Status Line Quality Standard PB IOTest ASR B46034 Liquid 0.5 mL GMP FITC IOTest ASR IM2716U Liquid 2 mL GMP PE IOTest ASR IM2717U Liquid 2 mL GMP IgE (D ε 2) The anti-IgE mAb binds to circulating IgE as well as to IgE antibodies bound to the low affinity receptor Fc ε RII (expressed mainly on eosinophils, B lymphocytes), or to the high affinity receptor Fc ε RI (expressed on mast cells, basophils, monocytes and monocytes-derived cells). The anti-IgE antibody induces the histamine release from basophils. However, it is known in the literature information that basophils from 10% to 20% of donors completely fail to release histamine in response to anti-IgE, designated anti-IgE "non releasers". Clone: 45.15

Lysed normal whole blood sample

Clone: E124.2.8 Isotype: IgG1 Mouse The E124.2.8 monoclonal antibody binds specifically to the D ε 2 constant domain of human Immunoglobulin E (IgE) (D ε 2 is the heat labile region of IgE).

Form

Size

Format

Part#

Status

Line Quality Standard

UNLB

A40174

0.2 mg

Freeze-dried

ASR

-

GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 110 US Clinical Diagnostics Catalog

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