Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD138 antigen (also known as syndecan-1) is a member of the syndecan family, which is comprised of 4 types of transmembrane heparan sulfate proteoglycans macromolecules (syndecan-1, -2 or fibroglycan, -3 or N-syndecan, and -4 or amphiglycan). These molecules are involved in interactions with extracellular matrix proteins, with cell-surface molecules and with soluble proteins such as cytokines. CD138 expression in human hematopoietic cells is restricted to plasma cells in normal bone marrow. Peripheral blood monocytes, T- and B-lymphocytes are not reactive. Tonsil cells and early B-cell precursors in human bone marrow also are negative. CD138 is expressed in a variety of mature tissues, including epithelial cells, endothelial cells, fibroblasts, keratinocytes and normal hepatocytes. CD138 may act as an essential regulator of ligand-specific activation of primary signalling receptors at the cell surface, by co-engagement of various accessory ligands. CD138

U266B1 cell line.

Form Clone: B-A38

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

B37788 B42019 A40316 A54190 A54191 A40317 A98835 B96786 A87787 B49219

0.5 mL 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP GMP

KrO

PE PE

2 mL

100 tests 100 tests

CE CE

98/79/EC 98/79/EC

PC5 PC5

1 mL

ASR ASR

GMP GMP

PC5.5 PC5.5

0.5 mL 50 tests 0.5 mL 50 tests

CE

98/79/EC

APC APC

ASR

GMP

CE

98/79/EC

CD141, also known as thrombomodulin (TM) and BDCA-3, is an endothelial cell surface receptor. It is a 75 kD type I membrane glycoprotein and members of C-type lectin family. Two major isoforms exist, differentiated by the presence or not of sulfated glycosaminoglycan at Ser/Thr region. CD141 antigen is expressed on neutrophils, monocytes and platelets. CD141 is expressed at high levels on a minor subpopulation of human myeloid dendritic cells that show monocytoid morphology. This subpopulation of dendritic cells is of special interest, because it has an influence on regulatory T cells and hence on immune responses. CD141 is also expressed by vascular endothelial cells, and keratinocytes. It is a cofactor in the activation of protein C and initiation of the protein C anticoagulant pathway by binding to its ligand thrombin. CD141 ( BDCA-3 )

Overlay - CD141-FITC K562 Transfected cell line

Form Clone: M80

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

B43289

1 mL

Liquid

ASR

IOTest

GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 90 Outside US Flow Cytometry Catalog