Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD126 antigen is the human IL-6 receptor α chain. It is an integral membrane protein of 80 kDa. In peripheral blood it is detectable on monocytes, on activated B lymphocytes, and on CD4+ T lymphocytes. This antigen is also expressed by epithelial cells. The CD126 antigen associates with CD130 to form a high affinity IL-6 receptor. A soluble form of CD126 (sIL-6R) can be detected in plasma. CD126 ( IL-6R α )

Lysed normal whole blood sample.

Clone: M91 Isotype: IgG1 Mouse The M91 antibody recognizes the membrane and soluble form of IL-6R α chain. It binds to the amino terminal immunoglobulin domain of IL-6R α . It binds to IL-6/IL-6R α complexes and IL-6/IL-6R/gp130 complexes. It is a non- blocking antibody suitable for Western blot assays.

Form

Size

Format

Part#

Status

Line Quality Standard

PE

IM1979

2 mL

Liquid

ASR

IOTest

GMP

The CD127 antigen is a 75-80 kDa type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7R α . It forms a heterodimer with the common γ chain CD132 (IL-2R γ ), which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21, to form the high affinity IL-7 receptor. CD127 is found on normal B cell precursors but not on mature B lymphocytes. It is also expressed by thymocytes, the majority of peripheral T lymphocytes, a subset of monocytes and a subset of CD34+ cells. CD127 is a useful marker for identifying memory and effector T cells. Its expression is down-modulated on Treg cells. The ligation of IL -7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development. CD127 ( IL-7R α )

Lysed normal whole blood sample.

Clone: R34.34

Isotype: IgG1 Mouse

The R34.34 antibody inhibits binding of IL-7 to CD127.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

B25366 IM1980U B49220 A64617 A64618 B42026 A71116 B12700

1 mL 2 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP GMP

PE PE

100 tests

CE

98/79/EC

PC5 PC7 APC

1 mL 1 mL

ASR ASR ASR ASR ASR

GMP GMP GMP GMP GMP

0.5 mL 0.5 mL 0.5 mL

APC-A700 APC-A750

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 87 Outside US Flow Cytometry Catalog