Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD116 antigen, a 75-85 kDa molecule, is the human Granulocyte-Monocyte Colony- Stimulating Factor (GM-CSF) receptor α chain. The CD116 antigen is not expressed by lymphocytes, but strongly by monocytes and granulocytes as well as their precursors. It is also present on endothelial cells, fibroblasts and Langerhans cells. CD116 associates with the common β chain (CDw131) of the IL-3 and IL-5 receptors to form a high affinity receptor for GM-CSF. CD116 ( GM-CSFR )

Lysed normal whole blood sample.

Clone: SCO6 Isotype: IgG1 Mouse The SCO6 antibody recognizes an epitope of the GM-CSF receptor α chain. It is a high affinity antibody which binds to the membrane and to the soluble form of GM-CSFR. It immunoprecipitates the molecule. SCO6 antibody does not work in Western blot assays.

Form

Size

Format

Part#

Status

Line Quality Standard

PE

IM1977

100 tests

Liquid

RUO

IOTest

GMP

The CD117 antigen, also known as Stem Cell Factor Receptor (SCFR), mast-cell-Kit, and steel factor receptor, is a 145 kDa transmembrane glycoprotein encoded by the ckit proto- oncogene. The CD117 molecule belongs to the class III Receptor Tyrosine Kinase (RTK) family. Within the haematopoeitic compartment, the CD117 molecule is expressed on approximately 50 % of CD34+ progenitors engaged in erythrocytic, myelo-monocytic and megakaryocytic differentiation. Although CD117 is primarily a marker for non-lymphoid progenitors, it has been reported to be detected on early lymphoid progenitors. CD117 expression has been found on a small subset of resting NK cells (CD56bright), and about 30% of immature CD3- CD4- CD8- thymocytes. CD117 is also expressed on mast cells and detected on non-hematopoietic cells such as reproductive system, melanocytes and embryonic brain cells. CD117 ( c-kit )

MO7E cell line.

Clone: 95C3 Isotype: IgG1 Mouse The 95C3 antibody reacts with BFU-E, CFU-GEMM, CFU-GM and CFU-G. The 95C3 antibody reduces the binding of SCF to its receptor to about half of the maximum value.

Form

Size

Format

Part#

Status

Line Quality Standard

PE

IM1360U IM2657U

2 mL 1 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PC5

Form Clone: 104D2D1

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PE PE

IM2732

100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

IM2732U B38307

2 mL

ASR ASR

GMP GMP

ECD PC5 PC5

0.5 mL

IM2733

100 tests

CE

98/79/EC

IM2733U A66333 B96754 IM3698 B49221 IM3638 B36300 A86051 B92450

1 mL

ASR ASR

GMP GMP

PC5.5 PC5.5

0.5 mL 50 tests

CE

98/79/EC

PC7 PC7 APC APC

1 mL

ASR

GMP

100 tests

CE

98/79/EC

1 mL

ASR

GMP

100 tests 0.5 mL 50 tests

CE

98/79/EC

APC-A750 APC-A750

ASR

GMP

CE

98/79/EC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 85 Outside US Flow Cytometry Catalog