Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD59 antigen, also known as Protectin or Membrane Inhibitor of Reactive Lysis (MIRL) is a 18-20 kDa, single-chain, glycosylphosphatidylinositol (GPI)-anchored cell surface protein. CD59 inhibits complement lysis by binding to the C5b-8 and C5b-9 complexes and thus preventing formation of the polymeric C9 complex during the final steps of membrane attack complex (MAC). CD59 is expressed on all haematopoietic cells and is widely expressed on cells in all tissues. Studies of the susceptibility of HIV-1, HTLV-1 and HCMV to complement (C)-mediated lysis suggest that viruses incorporate host cell-derived C regulatory proteins such as CD59 and CD55, a mechanism by which a variety of enveloped viruses may acquire resistance to C- mediated lysis. CD59

Lysed normal whole blood sample.

Form Clone: P282E

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC FITC

IM3457U

2 mL

Liquid Liquid

ASR

IOTest IOTest

GMP

B49187

100 tests

CE

98/79/EC

Form Clone: MEM-43

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

PE

B68140

1 mL

Liquid

ASR

IOTest

GMP

The CD61 antigen (platelet glycoprotein GPIIIa) is the 110 kDa integrin β 3 subunit, con- covalently associated with the integrin α IIb chain (CD41, platelet GPIIb) to form the GPIIb-IIIa complex ( α IIb- β 3 integrin). Independently of CD41, CD61 is also associated with the integrin α V (CD51) to form the vitronectin receptor. CD41/CD61 is expressed only by platelets and megakaryocytes, whereas CD51/CD61 is found on osteoclasts, endothelial cells, macrophages, fibroblasts, smooth muscle, synovial lining cells and renal glomeruli. CD61

Platelet rich plasma (PRP) from a normal whole blood sample.

Clone: SZ21 Isotype: IgG1 Mouse The SZ21 antibody is specific for the PlA1, not the PlA2 form of GPIIIa. It inhibits platelet aggregation and secretion induced by collagen, arachidonic acid, and thrombin. This antibody also inhibits fibrinogen binding to human platelets induced by ADP, arachidonic acid and PAF.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC FITC

IM1758

100 tests

Liquid Liquid Liquid Liquid Liquid

CE

IOTest IOTest IOTest IOTest IOTest

98/79/EC

IM1758U IM3605 B21172 IM3716 IM0540

2 mL 2 mL

ASR ASR ASR ASR RUO

GMP GMP GMP GMP GMP

PE

PC5.5

0.5 mL

PC7

1 mL

UNLB

0.2 mg

Freeze-dried

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If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 70 Outside US Flow Cytometry Catalog