Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD37 antigen is a 40-52 kDa single chain transmembrane protein with 4 transmembrane domains (Tetraspan/TM4SF). It has both its NH2- and COOH-termini inside the cells, and is heavily glycosylated on one extracellular loop. Its main feature is its high content of hydrophobic residues (45%). CD37 is strongly expressed on the surface of human peripheral blood B lymphocytes and on B cells from germinal centers. In the ontogeny of B cells, this antigen appears late, after the pre-B stage, and is not expressed on plasma cells. CD37 has a low expression on T lymphocytes, granulocytes, and monocytes. It is weakly expressed by other cellular types such as Langerhans cells, macrophages, normal medullar granulous cells and peripheral blood polymorphonuclear cells. CD37 is involved in signal transduction. CD37

Lysed normal whole blood sample.

Form Clone: BL14

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PE

IM0458

2 mL

Liquid

ASR

IOTest

GMP

The CD38 antigen is a 45 kDa single chain type II integral membrane glycoprotein, with the NH2-terminus inside the cytoplasm. CD38 is an enzyme with several activities such as NAD glycohydrolase, ADP ribosylcyclase and cyclic ADP ribose hydrolase. CD38 is expressed on activated T and B lymphocytes, NK cells, monocytes, plasma cells and medullary thymocytes. CD38 depends on the differentiation and activation of the cell. In the B cell lineage, CD38 is expressed in early stages of B-cell ontogeny, lost during maturation and re-expressed upon terminal differentiation to plasma cells. CD38 is expressed on thymocytes and at a high level on activated T cells. Most mature resting lymphocytes of both B and T lineages do not express the CD38 antigen. CD38 is widely used as a marker to study T and B lymphocyte activation. CD38

Lysed normal whole blood sample.

Form Clone: T16

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC FITC

A07778 IM0775U IM1832U

100 tests

Liquid Liquid Liquid

CE

IOTest IOTest IOTest

98/79/EC

2 mL 2 mL

ASR ASR

GMP GMP

PE

Form Clone: LS198-4-3

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB PB PE PE

B09683 B92396 A07779 IM2371U 6604928 A99022 A07780 IM2651U A70205 B49199 A54189 B49198 A60792 B23489 A86049 B49200

0.5 mL 50 tests 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

CE CE

98/79/EC 98/79/EC

2 mL

ASR ASR ASR

GMP GMP GMP

RD1 ECD PC5 PC5

0.5 mL 0.5 mL

CYTO - STAT

100 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

PC5.5 PC5.5

0.5 mL 50 tests 0.5 mL 50 tests 0.5 mL 0.5 mL 50 tests 1 mL

CE

98/79/EC

PC7 PC7 APC

ASR

GMP

CE

98/79/EC

ASR ASR ASR

GMP GMP GMP

APC-A700 APC-A750 APC-A750

CE

98/79/EC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 57 Outside US Flow Cytometry Catalog