Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD35 antigen is a polymorphic molecule. Different molecular weights: 160, 190, 220, 250 and 285 kDa were reported for the various allotypes. It is known as the complement receptor type I (CR1) with affinity for C3b, C4b and iC3b. The CD35 antigen is expressed by granulocytes (except basophils), B lymphocytes, a subset of T-cells, monocytes, some NK cells, erythrocytes macrophages cultured in vitro, glomerular podocytes and follicular dendritic cells. The CD35 antigen mediates phagocytosis by neutrophils and monocytes of complement coated particles. CD35

Lysed normal whole blood sample

Clone: J3D3 Isotype: IgG1 Mouse The J3D3 monoclonal antibody inhibits CR1-mediated decay of cells bound to the alternative and classical pathways to C3-convertase sites. It also inhibits C3b dependent rosette formation with lymphocytes.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

IM1836 IM0195

100 tests

Liquid

RUO RUO

IOTest

GMP GMP

UNLB

0.2 mg

Freeze-dried

-

The CD36 antigen (platelet GPIV, or GPIIIb) is a generic term for a family of glycoproteins with molecular weights ranging from 78 to 88 kDa. CD36 expression occurs in different types of cells, including mammary epithelial cells, endothelial cells monocytes, macrophages, platelets, megakaryocytes and early erythroid cells. This molecule is also found on some human tumor cell lines. It is a very early marker of erythroid differentiation and mediates the adherence of platelets to thrombospondin and collagen. CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA). As a result of its multiple ligands and signal transduction capabilities, CD36 has also a number of functions related to immune responses, inflammation and blood disorders. CD36

Lysed normal whole blood sample.

Clone: FA6.152 Isotype: IgG1 Mouse The FA6-152 monoclonal antibody, raised against fetal erythrocytes, recognizes the CD36 family of antigens on platelets and certain hematopoietic cells. It does not react with lymphocytes or granulocytes. It reacts with both fetal and adult monocytes, megakaryocytes, platelets, and with reticulocytes.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

B43302 IM0766U B49201 A87786 B46022 IM0765

0.5 mL

Liquid Liquid Liquid Liquid Liquid

ASR ASR

IOTest IOTest IOTest IOTest IOTest

GMP GMP

FITC FITC APC

2 mL

100 tests

CE

98/79/EC

0.5 mL 0.5 mL 0.2 mg

ASR ASR RUO

GMP GMP GMP

APC-A700

UNLB

Freeze-dried

-

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 56 Outside US Flow Cytometry Catalog