Flow Cytometry catalog - ROW 2019
Single-Color Conjugated Antibodies
The CD23 antigen (also called B6) is a transmembrane glycoprotein with a molecular weight of 45 kDa, spatially associated with the major histocompatibility complex (MHC) Class II antigen. The CD23 molecule, also named Fc ε RII is the low affinity receptor for IgE. CD23 antigen is primarily expressed on B lymphocytes and monocytes. It is also present on a large variety of other cells such as T lymphocytes, eosinophils, platelets, Langerhans cells, follicular dendritic cells (FDC), a subset of thymic epithelial cells and neutrophils. On B lymphocytes, CD23 expression is up-regulated upon activation and ultimately lost upon differentiation towards secreting-plasmocytes. A soluble form of CD23 (sCD23) exists and may be involved (like CD23) in the regulation of IgE synthesis and inflammatory phenomenom. CD23
Lysed normal whole blood sample.
Form Clone: HD50 (B6)
Isotype: IgG2b Mouse
Size
Format
Part#
Status
Line Quality Standard
RD1
6604426
0.5 mL
Liquid
ASR
CYTO - STAT
GMP
Clone: 9P25
Isotype: IgG1 Mouse
9P25 blocks the binding of IgE.
Form
Size
Format
Part#
Status
Line Quality Standard
PB
A93689 IM0529 IM0529U A33099 B49207 IM3609U B12935 A69964 A70207
0.5 mL
Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid
ASR
IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest
GMP
FITC FITC
100 tests
CE
98/79/EC
2 mL 2 mL
ASR ASR
GMP GMP
PE PE
100 tests
CE
98/79/EC
ECD PC7 APC
1 mL
ASR ASR ASR ASR
GMP GMP GMP GMP
0.5 mL
1 mL
APC-A700
0.5 mL
The CD24 antigen is a glycosyl-phosphatidylinositol-linked membrane sialoglycoprotein, with a molecular weight of 35-45 kDa. CD24 is present on B cells, from the pre-B to the mature B cell stage, but not on plasma cells. It is expressed on mature granulocytes and on a variety of epithelial cell types. CD24 was discovered in mice as a heat-stable antigen and was used as a marker to differentiate hematopoietic cells and neuronal cells. It is currently known that CD24 serves as a costimulatory factor of T cells that regulate their homeostasis and proliferation, while in B cells, CD24 is functionally involved in cell activation and differentiation. In hematopoietic cells, CD24 is known to bind to molecules exhibiting danger-associated molecular patterns (DAMPs). CD24 mediates signal transduction and activates the mitogen- activated protein kinase pathway, which involves B- and T-cell development and apoptosis, cell binding and granulocyte oxidative burst. CD24
Lysed normal whole blood sample.
Form Clone: ALB9
Isotype: IgG1 Mouse
Size
Format
Part#
Status
Line Quality Standard
PE PE
IM1428U B92425 B12699 IM2645 B23133 A87785 B10738
2 mL
Liquid Liquid Liquid Liquid Liquid Liquid Liquid
ASR
IOTest IOTest IOTest IOTest IOTest IOTest IOTest
GMP
100 tests
CE
98/79/EC
ECD PC5
0.5 mL
ASR ASR ASR ASR ASR RUO
GMP GMP GMP GMP GMP GMP
1 mL
PC5.5
0.5 mL 0.5 mL 0.5 mL 0.2 mg
APC
APC-A750
UNLB
IM0118
Freeze-dried
-
If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 49 Outside US Flow Cytometry Catalog
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