Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD19 antigen (also called B4) is a type I membrane glycoprotein with a molecular weight of 95 kDa. It is a signal transduction molecule that regulates lymphocyte development, activation, and differentiation. The molecule is expressed on all normal B lymphocytes including pro-B lymphocytes, but it is lost in maturation to plasma cells. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normal T lymphocytes, NK cells, monocytes, and granulocytes. CD19 can be associated with other surface molecules including CD21 and CD81. Co-ligation of the CD19-CD21-CD81 complex with the surface IgM-B-cell antigen receptor (BCR) leads to the phosphorylation of CD19 by Syk, followed by the recruitment of positive signal transduction effectors such as phosphatidylinositol 3 kinase (PI3 kinase), Lyn, and Fyn. CD19

Lysed normal whole blood sample.

Form Clone: 89B (B4)

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC FITC

6603012 6603859 6603024 6603846

Freeze-dried 100 tests

IVD & CE IVD & CE IVD & CE IVD & CE

GMP GMP GMP GMP

COULTER CLONE

50 tests 100 tests 50 tests

Liquid Liquid Liquid

CYTO - STAT

RD1 RD1

COULTER CLONE

CYTO - STAT

Clone: J3-119 Isotype: IgG1 Mouse In vitro studies show that the CD19 antibodies have an inhibitory effect on the activation and proliferation of B lymphocytes. They also inhibit the B cell response after co-stimulation by anti-immunoglobulin and interleukin 4.

Form

Size

Format

Part#

Status

Line Quality Standard

PB PB

A86355 B49213 A96418 A07768 IM1284U A07769 IM1285U A07770 IM2708U A07771 IM2643U A66328 IM3628U IM2470 IM2470U B76283 A78837 B49212 A78838 A94681 IM1313 B49211 IM3628

0.5 mL 50 tests 0.5 mL 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

CE

98/79/EC

KrO FITC FITC

ASR

GMP

CE

98/79/EC

2 mL

ASR

GMP

PE PE

100 tests

CE

98/79/EC

2 mL

ASR

GMP

ECD ECD PC5 PC5

100 tests

CE

98/79/EC

1 mL

ASR

GMP

100 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

PC5.5 PC5.5

0.5 mL 50 tests 100 tests

CE CE

98/79/EC 98/79/EC

PC7 PC7 APC APC

1 mL

ASR

GMP

100 tests

CE

98/79/EC

1 mL

ASR ASR ASR

GMP GMP GMP

AF700

0.5 mL 0.5 mL 50 tests 0.5 mL 50 tests 0.2 mg

APC-A700 APC-A700 APC-A750 APC-A750

CE

98/79/EC

ASR

GMP

CE

98/79/EC

UNLB

Freeze-dried

ASR

-

GMP

Form Clone: HD237 (B4 lytic)

Isotype: IgG2b Mouse

Size

Format

Part#

Status

Line Quality Standard

ECD

6604551

0.5 mL

Liquid

ASR

GMP

CYTO - STAT

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 46 Outside US Flow Cytometry Catalog