Flow Cytometry catalog - ROW 2019
Single-Color Conjugated Antibodies
CD11c (integrin α X subunit, also known as leucocyte surface antigen p150, Axb2 and CR4) is a member of the integrin family. Like other leucocyte integrins (CD11a, CD11b, CD11d), CD11c is non-covalently associated with the β 2 integrin subunit (CD18). CD11c is a transmembrane glycoprotein of 145-150 kDa, mainly expressed by monocytes, macrophages and NK cells, and to a lesser extent by granulocytes, dendritic cells and some subsets of T and B cells. CD11c / CD18 has an important role in cytotoxic T cell killing, in the adhesion of monocytes and neutrophils to the endothelium and induces cellular activation. The CD11c is ∼ 87% homologous in sequence to CD11b, and recognizes similar ligands including complement factor fragment iC3b, fibrinogen, CD54 and bacterial lipopolysaccharide. CD11c
Lysed normal whole blood sample.
Clone: BU15
Isotype: IgG1 Mouse
The BU15 antibody was used as a CD11c reference mAb (ref.6) during HLDA 6.
Form
Size
Format
Part#
Status
Line Quality Standard
PE PE
IM1760
100 tests
Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid
CE
IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest
98/79/EC
IM1760U IM3707 B19719 A80249 B96763 B01680 B43304
2 mL 1 mL
ASR ASR ASR ASR
GMP GMP GMP GMP
PC5
PC5.5
0.5 mL
PC7 PC7 APC
1 mL
100 tests
CE
98/79/EC
0.5 mL 0.5 mL
ASR ASR
GMP GMP
APC-A700
If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 40 Outside US Flow Cytometry Catalog
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