Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

CD11a ( α L integrin, LFA-1 α chain) is a member of the integrin family. Like some other leucocyte integrins (CD11b, CD11c, CD11d), CD11a is non-covalently associated with the β 2 integrin subunit CD18. CD11a is a transmembrane glycoprotein of 170 kDa, mainly expressed by leucocytes including monocytes, macrophages, neutrophils, eosinophils, basophils, B and T lymphocytes. Activated platelets also express CD11a and CD18. LFA-1 (CD11a/CD18) promotes homotypic adhesion between lymphoid cells and heterotypic adhesion of leucocytes to the vascular endothelium. LFA-1’s known ligands are Intercellular Adhesion Molecules (ICAM): ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50). CD11a

Lysed normal whole blood sample

Form Clone: 25.3

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

IM0860U IM1433U

2 mL 2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PE

The CD11b antigen is also known as the integrin α M subunit. It combines with the CD18 antigen (integrin β 2 subunit) to build the integrin Mac-1 (CD11b/CD18, α M β 2, CR3, iC3bR, Mo-1). CD11b is a type I transmembrane glycoprotein of 170 or 165 kDa under reducing or non-reducing conditions, respectively. CD11b shows 19 potential N-glycosylation sites. Expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen (also known as β 2 integrin chain). Together, these two subunits create the CD11b/CD18 integrin, one of the four integrin heterodimers that can be built by the association of CD18 β chain with four distinctive CD11 α chains. CD11b/CD18 is highly expressed on NK Cells, neutrophils, monocytes and macrophages. CD11b

Lysed normal whole blood sample.

Form Clone: 94 (Mo1)

Isotype: IgM Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

6602573

0.5 mg

Freeze-dried

ASR

GMP

COULTER CLONE

Clone: Bear1

Isotype: IgG1 Mouse

Bear1 is a non blocking monoclonal antibody.

Form

Size

Format

Part#

Status

Line Quality Standard

PB PB

B16891 B36296 IM0530 IM0530U IM2581U IM3611 A54822 A87782 A97052 B36295 IM0190

0.5 mL 50 tests 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

CE CE

98/79/EC 98/79/EC

FITC FITC

2 mL 2 mL 1 mL 1 mL

ASR ASR ASR ASR ASR ASR

GMP GMP GMP GMP GMP GMP

PE

PC5 PC7 APC

0.5 mL 0.5 mL 50 tests 0.2 mg

APC-A750 APC-A750

CE

98/79/EC

UNLB

Freeze-dried

ASR

-

GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 39 Outside US Flow Cytometry Catalog