Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

Along with CD8 α , the CD8 β polypeptide molecule is one of the two chains which can be expressed within the CD8 dimer. CD8 α is required for surface expression of CD8 β . The α and β glycoproteins have similar molecular weights of 32-34 kDa each. They form homodimeric (CD8 α / α ) or heterodimeric (CD8 α / β ) cell surface complexes. Most of human peripheral T cells express CD8 as an α / β heterodimer. NK cells and a proportion of TCR γ / δ T cells express CD8 as an α / α homodimer. CD8 β surface expression requires the surface expression of CD8 α . Consequently, CD8 α can form homodimer but CD8 β cannot. CD8 β Form Isotype: IgG2a Mouse The 2ST8.5H7 monoclonal antibody reacts with an epitope formed by the combination of the α and β polypeptides. Part# Format Size Status Line Quality Standard FITC IOTest ASR B42025 Liquid 1 mL GMP PE IOTest ASR IM2217U Liquid 2 mL GMP ECD IOTest RUO 6607123 Liquid 100 tests GMP UNLB - RUO IM2014 Freeze-dried 0.2 mg GMP CD9 (p24 antigen) is a single transmembrane polypeptide of 24 kDa related to the tetraspanin (TM4) family. Like other tetraspanins (e.g. CD63, CD81, CD82, CD37, CD53, among the 20 known members), CD9 structure is composed of 4 transmembrane domains, with intracellular N and C termini. First discovered on a lymphoblastic cell line of pre-B phenotype, CD9 was then found on platelets and within their α -granules, on monocytes, pre-B cells, eosinophils, basophils and activated T cells. The CD9 molecule associates with other surface proteins such as the α 6/ β 4 integrin (CD49f/CD104 molecule) and HLA-DR, suggesting a role in adhesion, signal transduction and cell motility. CD9 Clone: 2ST8.5H7

Lysed normal whole blood sample.

Platelet-rich plasma (PRP) from normal whole blood.

Clone: ALB6 Isotype: IgG1 Mouse The ALB6 monoclonal antibody (mAb) was first reported as specific for CD9 (p24) on platelets, capable of modulating aggregation of platelets activated with various agonists.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

B09979 IM1755U B13649

0.5 mL

Liquid Liquid Liquid

ASR ASR ASR RUO

IOTest IOTest IOTest

GMP GMP GMP GMP

FITC

2 mL

APC-A750

0.5 mL 0.2 mg

UNLB

IM0117

Freeze-dried

-

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 37 Outside US Flow Cytometry Catalog