Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8 α homodimer or as a CD8 α / β heterodimer. CD8 α is required for surface expression of CD8 β . The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain ( α 3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8 α homodimer is expressed by NK cells and γ / δ + T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes. CD8

Lysed normal whole blood sample.

Clone: B9.11 Isotype: IgG1 Mouse The B9.11 monoclonal antibody recognizes the α chain of the CD8 molecule. It was used as a CD8 reference monoclonal antibody during HLDA 6 (ref. 6T-CD8.5).

Form

Size

Format

Part#

Status

Line Quality Standard

PB PB

A82791 B49182 B00067 A07756 IM0451U A07757 IM0452U B08467 A07758 IM2638U B21205 IM2469 IM2469U B76279 A66332 B49181 A94683 A94686 6602385 6603861 6603274 6603848 6604728 737659 6607011 A99019 6607102 737661 A99023

0.5 mL 50 tests 0.5 mL 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

CE

98/79/EC

KrO FITC FITC

ASR

GMP

CE

98/79/EC

2 mL

ASR

GMP

PE PE

100 tests

CE

98/79/EC

2 mL

ASR ASR

GMP GMP

ECD PC5 PC5

0.5 mL

100 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

PC5.5

0.5 mL

APC APC

100 tests

CE

98/79/EC

1 mL

ASR ASR ASR

GMP GMP GMP

AF700

0.5 mL 0.5 mL 50 tests 50 tests 0.5 mL

APC-A700 APC-A700 APC-A750 APC-A750

CE CE

98/79/EC 98/79/EC

ASR

GMP

Clone: SFCI21Thy2D3 (T8)

Isotype: IgG1 Mouse

Form SFCI21Thy2D3 monoclonal antibody recognizes the α chain of the CD8 molecule. Part# Format Size Status

Line Quality Standard

FITC FITC RD1 RD1 ECD ECD PC5 PC7 PC7 APC PC5.5

Freeze-dried 100 tests

IVD & CE IVD & CE IVD & CE IVD & CE

GMP GMP GMP GMP GMP GMP GMP GMP

COULTER CLONE

50 tests 100 tests 50 tests 0.5 mL 50 tests 0.5 mL 0.5 mL 100 tests 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CYTO - STAT

COULTER CLONE

CYTO - STAT CYTO - STAT CYTO - STAT CYTO - STAT

ASR

CE

98/79/EC

ASR ASR RUO

IOTest IOTest IOTest IOTest

CE

98/79/EC

0.5 mL

ASR

GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 36 Outside US Flow Cytometry Catalog