Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD6 antigen is a single-chain type I transmembrane glycoprotein with three extracellular SRCR domains. It exists predominantly in two isoforms as 100 kDa and 130 kDa. CD6 is an extensively glycosylated molecule and differences in glycosylation patterns may occur. The CD6 molecule is modified by phosphorylation of serine, threonine and tyrosine residues during T-cell activation. CD6 have a role as a costimulatory molecule for T-cell activation and in cell adhesion. CD166 was identified as an adhesion receptor for CD6. The CD6 antigen is expressed on the surface of most mature human T cells and a subset of resting B cells and medullary thymocytes. It is found on NK cells not it is reported to be on any other cells. CD6

Lysed normal whole blood sample.

Form Clone: 2H46D3B

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

FITC

B16492

1 mL

Liquid

ASR

IOTest

GMP

The CD7 antigen is a membrane-embedded glycoprotein with a molecular weight of 40 kDa. It is expressed at an early stage of T lineage ontogeny, during the extrathymic prothymocytic formation. CD7 expression persists throughout T lymphocytes differentiation defining CD7 as a pan-T marker. It is also expressed on thymocytes, on the majority of resting T lymphocytes, and Natural Killer cells (NK), and on a subset of pre-B lymphocytes and B lymphocytes from foetal bone marrow. CD7 expression is also detected on pluripotent hematopoietic stem cells. Mature B-lymphocytes, cells from erythroid, myeloid and megacaryocytic lineage do not express the CD7 molecule. The CD7 molecule is involved in T lymphocytes activation. Its expression may be quantitatively up-regulated on stimulated T lymphocytes. CD7

Lysed normal whole blood sample.

Clone: 3A1E-12H7

Isotype: IgG2b Mouse

3A1E-12H7 (ref. 6T-CD7.4) was used as a CD7 reference monoclonal antibody during HLDA 6.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

6603824 6603822 6603827

0.5 mL 0.5 mL 0.5 mL

Liquid Liquid Liquid

ASR ASR ASR

CYTO - STAT CYTO - STAT

GMP GMP GMP

RD1 RD1

COULTER CLONE

Form Clone: 8H8.1

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

B06499 A07755 IM0585U IM1429U A70202 IM3613U A46526 B49183 A97050 A70201 B36290 B16892 IM3613

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

FITC FITC

100 tests

CE

98/79/EC

2 mL 2 mL 1 mL

ASR ASR ASR

GMP GMP GMP

PE

ECD PC5 PC5 PC7 PC7 APC

100 tests

CE

98/79/EC

1 mL 1 mL

ASR ASR

GMP GMP

100 tests 0.5 mL 0.5 mL 50 tests 0.5 mL

CE

98/79/EC

ASR ASR

GMP GMP

APC-A700 APC-A700 APC-A750

CE

98/79/EC

ASR

GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 35 Outside US Flow Cytometry Catalog