Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

CD5 is a type I transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of nearly 100 amino acids each. The CD5 is expressed at the surface of mature T lymphocytes, by most of thymocytes and by a subpopulation of B lymphocytes (B-1a) expanded in neonatal life, several autoimmune disorders and some B-cell proliferative disorders (B-CLL). It is not found on granulocytes, monocytes and platelets. The CD5 antigen is the ligand for the B-lymphocytes cell-surface protein CD72. The CD5 / CD72 interactions are involved in the regulation of T and B lymphocyte activation and proliferation. B lymphocytes can be divided into B-1 lymphocytes and B-2 (or conventional B) lymphocytes based on different localization, functional characteristics and gene expression. The B-1 lymphocyte subset is divided into B-1a and B-1b subpopulations, which do or do not express the CD5 antigen respectively. The B-1a CD5+ B lymphocyte subset expresses immunoglobulin with inherent low affinities for self-antigens. CD5

Lysed normal whole blood sample.

Clone: BL1a

Isotype: IgG2a Mouse

BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA / 6.

Form

Size

Format

Part#

Status

Line Quality Standard

PB

A82790 A08932 IM0468U A07753 IM0469U A33096 A07754 IM2637U A70203 B49191 A51075 A21690 A60790 A78835 A78836 B92413

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

FITC FITC

100 tests

CE

98/79/EC

2 mL

ASR

GMP

PE PE

100 tests

CE

98/79/EC

2 mL 1 mL

ASR ASR

GMP GMP

ECD PC5 PC5

100 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

PC5.5 PC5.5

0.5 mL 50 tests

CE

98/79/EC

PC7 PC7 APC

1 mL

ASR

GMP

100 tests

CE

98/79/EC

1 mL

ASR ASR ASR

GMP GMP GMP

APC-A700 APC-A750 APC-A750

0.5 mL 0.5 mL 50 tests

CE

98/79/EC

Form Clone: CLB-T1/1

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

ECD APC

B55387 B55386

0.5 mL 0.5 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 34 Outside US Flow Cytometry Catalog