Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD4 antigen is a monomeric transmembrane glycoprotein with a molecular weight of 59 kDa. The intracytoplasmic tail of CD4 is essential for interaction with Lck. The CD4 is expressed on the T "helper" (Th or T4) lymphocytes. It is expressed on most thymocytes, where it is frequently co-expressed with CD8. CD4 is also expressed on eosinophils. All the monocytes carry the CD4 antigen, but at a lower density than T4 lymphocytes. CD4 acts as an accessory molecule to the T cell receptor complex during T-cell activation restricted to the major histocompatibility complex class II. The T4 lymphocytes are involved in T-T, T-B, and B- macrophage cellular interactions. They are active in inducing and helping the synthesis of immunoglobulins by B cells. CD4 functions as the receptor for IL-16 which is a chemoattractant factor for CD4+ T cells, as well as for monocytes and eosinophils. IL-16 seems to be a growth factor for T4 lymphocytes, but is not able to induce cell division. CD4 is a receptor for the Human Immunodeficiency Virus type I (HIV-1) envelope protein gp120. CD4 Isotype: IgG1 Mouse 13B8.2 monoclonal antibody antagonizes HIV effects in vitro . 13B8.2 recognizes an epitope close to the amino-acid residues 88-89 within the CD4 molecule. 13B8.2 and BL4 recognize different epitopes. 13B8.2 and BL4 are not cross- blocking. Clone: 13B8.2

Lysed normal whole blood sample.

Form

Size

Format

Part#

Status

Line Quality Standard

PB PB

A82789 B49197 A96417 A07750 IM0448U IM0449U A07752 IM2636U B16491 IM2468 IM2468U B10824 A94682 A94685 IM0704 IM0398 A07751

0.5 mL 50 tests 0.5 mL 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

CE

98/79/EC

KrO FITC FITC

ASR

GMP

CE

98/79/EC

2 mL

ASR

GMP

PE PE

100 tests

CE

98/79/EC

2 mL

ASR

GMP

PC5 PC5

100 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

PC5.5

0.5 mL

APC APC

100 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

APC-A700 APC-A750 APC-A750

0.5 mL 50 tests 0.5 mL 0.2 mg 0.2 mg

CE

98/79/EC

ASR ASR ASR

GMP GMP GMP

Biotin UNLB

Freeze-dried Freeze-dried

- -

Clone: SFCI12T4D11 (T4)

Isotype: IgG1 Mouse

SFCI12T4D11 monoclonal antibody antagonizes HIV effects in vitro .

Form

Size

Format

Part#

Status

Line Quality Standard

FITC FITC RD1 RD1 ECD PC7 PC7

6602393 6603862 6602864 6603850 6604727 6607101 737660

Freeze-dried 100 tests

IVD & CE IVD & CE IVD & CE IVD & CE

GMP GMP GMP GMP GMP GMP

COULTER CLONE

50 tests 100 tests 50 tests

Liquid Liquid Liquid Liquid Liquid Liquid

CYTO - STAT

COULTER CLONE

CYTO - STAT CYTO - STAT

0.5 mL

ASR RUO

100 tests 100 tests

IOTest IOTest

CE

98/79/EC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 33 Outside US Flow Cytometry Catalog