Flow Cytometry catalog - ROW 2019

DURActive Panels

Size

RUO Status

Part #

DURActive 2

C11102

25 tests

Dry Stimulation Mixes for Immune Functional Assays Phorbol-Myristate-acetate (PMA) and Ionomycin are broad cellular activators of human leukocytes. A mix of these 2 compounds strongly activates leukocytes, hence it can serve e.g.: As a positive control in leukocyte (ligand-specific) functional assays or as a nonspecific activator in leukocyte functional subtyping experiments (e.g. for inducing NET formation and NADPH -oxidase activity in Neutrophils).

The DURActive stimulation kits contain optimally dosed physiologically active compounds provided as unitized single tests in 12x75 mm tube format.

Components

Phorbol 12-myristate 13 acetate (PMA)

Ionomycin calcium salt from Streptomyces conglobatus

Size

RUO Status

Part #

DURActive 3

C21857

25 tests

Dry Stimulation Mixes for Immune Functional Assays Lipopolysaccharide (LPS), a constituent of the membrane of gram-negative bacteria, represents a pathogen-associated molecular pattern (PAMP). Brefeldin A blocks Golgi-apparatus-mediated secretion. A mix of these 2 compounds strongly activates cells of the innate immune system expressing LPS-recognizing surface receptors such as monocytes, and traps newly synthesized biomolecules (e.g., cytokines) inside the cell, indicating the capacity to respond to microbial pathogens.

The DURActive stimulation kits contain optimally dosed physiologically active compounds provided as unitized single tests in 12x75mm tube format.

Components

Lipopolysaccharides from Escherichia coli O127:B8

Brefeldin A

Not available in all geographies. DURActive products are available for Research Use Only. Not for use in diagnostics procedures.

ANTIBODIES & KITS

184

Outside US Flow Cytometry Catalog