Flow Cytometry catalog - ROW 2019

DURAClone

Size

Status

Part #

DURAClone RE PC Tube

B80394

25 tests

RUO

Detection of CD45 + CD38 + CD138 + CD56 + CD200 + CD19 - CD27 - CD81 - plasma cells.

Human plasma cells (CD45+CD38+CD138+) express high density levels of the antigens CD19, CD27 and CD81 on their surface. In contrast, the antigens CD56 and CD200 are expressed at low density levels or are even completely absent. Deviation from these patterns involving high expression of CD56 and/or elevated expression of CD200 often accompanied by reduced expression densities or even absence of CD19 and/or CD27 and/or CD81 and/or CD45 can be utilized to identify abnormal plasma cells even at very low frequencies.

The DURAClone RE PC tube is an 8-color, 8-monoclonal antibody reagent that allows the identification of abnormal plasma cells in human bone marrow samples post red blood cell lysis. It contains 3 Compensation Kits, each kit containing eight tubes, each of a single color: CD4-FITC; CD4-PE; CD19-PC5.5; CD200-PC7; CD4-APC; CD56- APC-A750; CD4-PB; CD8-Krome Orange. All tandem dye-labeled antibodies are lot-matched.

Specificity

Fluorochrome

Clone (Isotype)

CD38

Pacific Blue*

LS198-4-3 (IgG1 Mouse)

CD45

Krome Orange

J33 (IgG1 Mouse)

CD81

FITC

JS64 (IgG2a Mouse)

CD27

PE

1A4CD27 (IgG1 Mouse)

CD19

PC5.5

J3-119 (IgG1 Mouse)

CD200

PC7

OX-104 (IgG1 Mouse)

CD138

APC

B-A38 (IgG1 Mouse)

CD56

APC-Alexa Fluor* 750

N901 (IgG1 Mouse)

Not available in all geographies. DURAClone IF, IM, RE and SC Panels are available for Research Use Only. Not for use in diagnostics procedures.

ANTIBODIES & KITS

180

Outside US Flow Cytometry Catalog