Flow Cytometry catalog - ROW 2019

DURAClone

Size

Status

Part #

DURAClone IF Monocyte Activation Tube

C21858

25 tests

RUO

Assessment of innate immune competency in monocytes Monocyte activation in response to infections is initiated when there is interaction between the pattern recognition receptors (PRRs) and pathogen-associated molecular patterns (PAMPs). This activation leads to the differentiation of the monocytes to macrophages or myeloid dendritic cells and an increase in their ability to phagocytose, present antigen and release proinflammatory cytokines. The increased functionality

of CD14+ monocytes can be correlated with increased production of TNF α . The DURAClone IF Monocyte Activation tube is a 4-color reagent that allows to assess HLA-DR expression and TNF α production in monocytes. The selected antibody conjugate configuration does not require compensation.

Specificity

Fluorochrome

Clone (Isotype)

CD14

Pacific Blue*

RMO52 (IgG2a Mouse)

CD45

Krome Orange

J33 (IgG1 Mouse)

HLA-DR

PE

Immu-357 (IgG1 Mouse)

TNF α

Alexa Fluor* 700

IPM2 (IgG1 Mouse)

Lysed normal whole blood sample

Not available in all geographies. DURAClone IF, IM, RE and SC Panels are available for Research Use Only. Not for use in diagnostics procedures.

ANTIBODIES & KITS

178

Outside US Flow Cytometry Catalog