Flow Cytometry catalog - ROW 2019

DURAClone

Size

Status

Part #

DURAClone IF T Helper Cell

C04666

25 tests

RUO

Detection of Th1/Th2/TH17 signature cytokines in T helper cells CD4 + T cells represent the majority of T lymphocytes in the secondary lymphoid organs. They preferentially recognize HLA Class II and their activation leads to their differentiation into subsets depending on the context of the stimuli. Activated CD4 + T cell subsets can be identified by their signature cytokines like IL-4, IL-17A and/or IFN- γ which are important for their helper cell functions.

The DURAClone IF T Helper Cell tube is a 5-color reagent that allows to identify IFN γ -, IL-4- and IL-17A-secreting CD4 + T helper cell subsets (Th1, Th2, Th17). It contains 3 compensation Kits, each containing five tubes, each of a single color: CD4-FITC; IL4-PC7; CD4-APC; CD3-AF750; CD4-PB. All tandem dye- labeled antibodies are lot-matched.

Specificity

Fluorochrome

Clone (Isotype)

IL-17A

Pacific Blue*

BL168 (IgG1 Mouse)

IFN- γ

FITC

45.15 (IgG1 Mouse)

IL-4

PC7

MP4-25D2 (IgG1 Rat)

CD4

APC

13B8.2 (IgG1 Mouse)

CD3

Alexa Fluor* 750

UCHT1 (IgG1 Mouse)

Not available in all geographies. DURAClone IF, IM, RE and SC Panels are available for Research Use Only. Not for use in diagnostics procedures.

ANTIBODIES & KITS

176

Outside US Flow Cytometry Catalog