Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

Also called TCRBV11S1 V β 11 is the human variable β 11 chain of the T cell receptor. Two V β 11 sequences are described, PL3.12 and PH15. These sequences differ only in their leader sequence and therefore lead to the same mature protein. An invariant V α 24/V β 11 T cell receptor is expressed in all individuals by clonal expanded CD4– CD8– T cells, reactive to bacterial antigens. This unique lymphocyte population restricted by the CD1d molecule recognition has been identified as the natural killer T (NKT) cells. V β 11 is expressed by 0.4% to 0.9% of peripheral CD3+ cells in normal blood. This sequence is also referred to as TRBV25-1 (based on the IMGT gene nomenclature). TCR V β 11

Tri Vbeta 11 Cell line.

Clone: C21 Isotype: IgG2a Mouse The C21 recognizes the gene product of PL3.12 and PH15 sequences. The specificity of this antibody has been confirmed at the First Human TcR Monoclonal Antibody Workshop in San Francisco in 1995.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

IM1586 IM2290 A66905

1 mL 1 mL

Liquid Liquid Liquid

ASR ASR ASR

IOTest IOTest IOTest

GMP GMP GMP

PE

APC

0.5 mL

Also called TCRBV12S1 V β 12 is a family of the T cell receptor. It is expressed by 1.1% to 1.9% of peripheral CD3+ cells in normal blood. This sequence is also referred to as TRBV10-3 (based on the IMGT gene nomenclature). TCR V β 12

NT12.2.1 Cell line.

Clone: VER2.32.1 Isotype: IgG2a Mouse The VER2.32.1 monoclonal antibody recognizes HBP54 identical to PH27 sequence often referred to as V β 12.2. The reactivity of the other members of this family (PL4.2 sequence) and other recently described V β 12 genes (HT96 sequence) has not been found but cannot be formally excluded.

Form

Size

Format

Part#

Status

Line Quality Standard

FITC

IM1587 IM2291

1 mL 1 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

PE

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 134 Outside US Flow Cytometry Catalog

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