Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

IL17-A is a member of the IL-17 family which is constituted by 6 members (IL-17A to IL-17F). IL -17A is commonly refer to as IL-17 and is produced as a homodimer of about 30 kDa. IL-17A is mainly secreted by a subset of CD4 + T cells, namely the Th17 cells, which are helper cells that are distinct from Th1 and Th2 cells. In addition to Th17 cells, other immune cells such as γδ T cells, CD8+ T cells, NK cells and Innate Lymphoid cells (ILCs) can be activated to secrete IL-17. IL-17 is a pro-inflammatory molecule that induces the production of chemokines and other cytokines by various cell types, i.e fibroblasts, epithelial cells, endothelial cells, macrophages and neutrophils, which helps the recruitment of innate immune cells at the site of activation. IL-17A

Peripheral blood lymphocytes (PBL) activated with PMA/Ionomycin/Brefeldin A, permeabilized and fixed with PerFix-nc reagent.

Form Clone: BL168

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB

B76266 B90428

50 tests 50 tests

Liquid Liquid

RUO RUO

IOTest IOTest

GMP GMP

AF700

Kappa ( κ ) chain is a 25Kd polypeptide that results from papain cleavage of the IgG molecule, encoded by the human immunoglobulin kappa locus (IGK) on chromosome 2. The subunit structure of IgG comprises 2 light chains and 2 heavy chains. Each light chain is composed of two tandem immunoglobulin domains: a) one variable domain (VL) and b) one constant (CL) domain. While the VL show considerable sequence diversity the CL shows internal homology with repeating units. Anti-Kappa antibodies recognize the Kappa light chain of immunoglobulins expressed at the surface of a cellular subpopulation corresponding to approximately 2/3 of mature B lymphocytes in peripheral blood. This light chain is also found on the surface of a sub-population of immature bone marrow B lymphocytes. κ Chain

Lysed normal whole blood sample

Clone: Polyclonal

Isotype: F(ab’) 2

Goat

Form

Size

Format

Part#

Status

Line Quality Standard

FITC APC

C15623 B90420

2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

GMP GMP

0.5 mL

Clone: Polyclonal

Isotype: F(ab’) 2

Rabbit

Form

Size

Format

Part#

Status

Line Quality Standard

FITC FITC

A64828 B49178

2 mL

Liquid Liquid

ASR

IOTest IOTest

GMP

100 tests

CE

98/79/EC

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 121 Outside US Flow Cytometry Catalog