Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The human major histocompatibility complex (MHC), also called human leucocyte antigens (HLA), is composed of three groups of molecules designated MHC class I, class II and class III. The MHC class II genomic region, or HLA-D region, contains the genes encoding HLA-DR, -DQ and -DP antigens. The MHC class II molecules are built by the non-covalent association of α / β heterodimers. Both heavy ( α ) and light ( β ) chains span the cell membrane. They have molecular weights of 31-33 kDa and 26-29 kDa respectively. HLA-DR molecules are found on antigen-presenting cells (APC), i.e. dendritic cells, B lymphocytes, monocytes, macrophages, Langerhans cells and thymic epithelial cells. They are also expressed on activated T cells, but not on granulocytes, platelets, or red blood cells. Resting T cells or endothelial cells that do not normally express these molecules can be induced to express them. HLA-DR is also expressed on some hematopoietic progenitor cells at different stages of differentiation. HLA-DR Isotype: IgG2b Mouse HLA-DR antibodies are specific to non polymorphic determinants of human HLA class II DR molecules which are constituted of α and β polypeptides of 34 and 29 kDa respectively. Part# Format Size Status Line Quality Standard FITC IOTest ASR IM0463U Liquid 2 mL GMP PE IOTest ASR IM0464U Liquid 2 mL GMP Form Clone: B8.12.2

Lysed normal whole blood sample.

Form Clone: Immu-357

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB PB

A74781 B36291 B00070 IM1638U B96758 IM1639U IM3636 B92438 A07793 IM2659U B20024 A40579 B49180 IM3635 B42021 IM1639

0.5 mL 50 tests 0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

GMP

CE

98/79/EC

KrO FITC FITC

ASR ASR

GMP GMP

2 mL

100 tests 100 tests

CE CE

98/79/EC 98/79/EC

PE PE

2 mL 1 mL

ASR ASR

GMP GMP

ECD ECD PC5 PC5 PC7 PC7 APC

100 tests 100 tests

CE CE

98/79/EC 98/79/EC

1 mL

ASR ASR ASR

GMP GMP GMP

PC5.5

0.5 mL 0.5 mL 50 tests

CE

98/79/EC

1 mL

ASR ASR

GMP GMP

APC-A750

0.5 mL

HLA-DR, DP, DQ The recognized epitope is specific to a non-polymorphic HLA class II (DR, DP, DQ) Ia antigen constituted of α and β polypeptides of 34 and 29 kDa respectively. This antigen is expressed on monocytes, macrophages, B lymphocytes and activated T lymphocytes.

Form Clone: 9-49 (I3)

Isotype: IgG2a Mouse

Size

Format

Part#

Status

Line Quality Standard

RD1

6604366

0.5 mL

Liquid

ASR

GMP

CYTO - STAT

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 117 Outside US Flow Cytometry Catalog