Flow Cytometry catalog - ROW 2019

Single-Color Conjugated Antibodies

The CD203c molecule is a type II transmembrane protein that belongs to the ectonucleotide pyrophosphatase / phosphosdiesterase 3 (E-NPP3) family of enzymes involved in hydrolysis of oligonucleotides, nucleoside phosphates, and NAD. Basophils and mast cells are hematopoietic effector cells involved in allergic and inflammatory reactions. Both cell types highly express the high affinity IgE receptor. The CD203c is expressed on human peripheral blood basophils, but not on other blood cells. It is also expressed by mature mast cells, and by CD34+ bone marrow progenitors of basophils and mast cells. Moreover, the CD203c antigen is up-regulated after activation of basophils by anti-IgE antibodies and allergens. CD203c

KU812 Cell line.

Clone: 97A6 Isotype: IgG1 Mouse The 97A6 antibody immunoprecipitates two proteins of 270 and 150 kDa at reducing conditions, and one protein of 270 kDa at nonreducing conditions, suggesting that the 97A6 antigen is a disulfide-linked dimer of two proteins of about 150 kDa each.

Form

Size

Format

Part#

Status

Line Quality Standard

PE PE

IM3575 B92404 A66906

2 mL

Liquid Liquid Liquid

ASR

IOTest IOTest IOTest

GMP

100 tests

CE

98/79/EC

PC7

1 mL

ASR

GMP

CD206, also named macrophage mannose receptor (MMR), is a type I single-chain transmembrane glycoprotein of 175 kDa with a multilectin receptor structure. The Mannose Receptor is thought to play a key role in the internalization of sugar-containing proteins thus concentrating antigens for transport to processing compartments and peptide loading compartments. First detected on tissue macrophages, the Mannose Receptor is mainly expressed on immature dendritic cells and on a variety of other cells. Absent on lymphocytes and monocytes, the Mannose Receptor is up-regulated on monocytes during their differentiation to macrophages. CD206 ( MMR )

Dendritic cells from in vitro activated density-purified whole blood sample (PBL).

Form Clone: 3.29B1.10

Isotype: IgG1 Mouse

Size

Format

Part#

Status

Line Quality Standard

PB PE

B36119 IM2741 B36120

0.5 mL

Liquid Liquid Liquid

ASR ASR ASR

IOTest IOTest IOTest

GMP GMP GMP

2 mL

PC7

0.5 mL

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 101 Outside US Flow Cytometry Catalog