2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

The CD116 antigen, a 75-85 kDa molecule, is the human Granulocyte-Monocyte Colony-Stimulating Factor (GM-CSF) receptor α chain. The CD116 antigen is not expressed by lymphocytes, but strongly by monocytes and granulocytes as well as their precursors. It is also present on endothelial cells, fibroblasts and Langerhans cells. CD116 associates with the common β chain (CDw131) of the IL-3 and IL-5 receptors to form a high affinity receptor for GM-CSF. CD116 ( GM-CSFR )

Lysed normal whole blood sample.

Clone: SCO6 (IgG1 Mouse) The SCO6antibodyrecognizesan epitopeof the GM-CSFreceptor

α chain.It is a highaffinityantibodywhichbindsto the membraneand to the solubleformof

GM-CSFR. It immunoprecipitates the molecule. SCO6 antibody does not work in Western blot assays.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE

IM1977

100 tests

Liquid

RUO

IOTest

cGMP

The CD117 antigen, also known as Stem Cell Factor Receptor (SCFR), mast-cell-Kit, and steel factor receptor, is a 145 kDa transmembrane glycoprotein encoded by the ckit proto-oncogene. The CD117 molecule belongs to the class III Receptor Tyrosine Kinase (RTK) family. Within the haematopoeitic compartment, the CD117 molecule is expressed on approximately 50 % of CD34+ progenitors engaged in erythrocytic, myelo-monocytic and megakaryocytic differentiation. Although CD117 is primarily a marker for non-lymphoid progenitors, it has been reported to be detected on early lymphoid progenitors. CD117 expression has been found on a small subset of resting NK cells (CD56bright), and about 30% of immature CD3- CD4- CD8- thymocytes. CD117 is also expressed on mast cells and detected on non-hematopoietic cells such as reproductive system, melanocytes and embryonic brain cells. CD117 ( c-kit )

MO7E cell line.

Clone: 95C3 (IgG1 Mouse) The 95C3 antibodyreactswith BFU-E,CFU-GEMM,CFU-GMand CFU-G.The 95C3 antibodyreducesthe bindingof SCF to its receptorto about half of the maximum value.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE

IM1360U IM2657U

2 mL 1 mL

Liquid Liquid

ASR ASR

IOTest IOTest

cGMP cGMP

PC5

Clone: 104D2D1 (IgG1 Mouse) 104D2D1 cross reacts with: Bovine.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE PE

IM2732

100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

IM2732U B38307

2 mL

ASR ASR

cGMP cGMP

ECD PC5 PC5

0.5 mL

IM2733

100 tests

CE/IVD

98/79/EC

IM2733U B96754 A66333 B49221 IM3698 B36300 IM3638 B92450 A86051

1 mL

ASR

cGMP

PC5.5 PC5.5

50 tests 0.5 mL 100 tests

CE/IVD

98/79/EC

ASR

cGMP

PC7 PC7 APC APC

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

APC-A750 APC-A750

50 tests 0.5 mL

CE/IVD

98/79/EC

ASR

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 84 Outside US Flow Cytometry Catalog