2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD105

The CD105 antigen, also called Endoglin, is a 170-180 kDa RGD containing molecule which is present on the cell surface as a disulphide-linked homodimer. The molecule is a co-receptor for Transforming Growth Factor (TGF) β 1 and β 3. It is expressed mainly on endothelial cells, but also strongly in pre-B lymphocytes and in a subpopulation of monocytes. CD105 is a regulatory protein of TGF-beta receptor complex. CD105 expression and function in primitive hematopoiesis indicate that this molecule could cooperate with the dissociation of TGF- β 1 cell cycle effects from its other effects on cell survival and differentiation.

KG1A Cell line.

Clone: TEA3/17.1.1 (IgG1 Mouse)

Form

Format

Part#

Status

Line

Quality Standard

Size

PE PE

B92442 B76299 B43293

50 tests

Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest

98/79/EC

1 mL

ASR ASR

cGMP cGMP

PC7

0.5 mL

CD106

The CD106 antigen, also known as Vascular Cell Adhesion Molecule-1 (VCAM-1), is an adhesion molecule which binds to integrin α 4/ β 1 (VLA-4) and integrin α 4/ β 7 on lymphocytes. It is a 110 kDa cell surface sialoglycoprotein belonging to the immunoglobulin superfamily. CD106 contains 7 Ig-like C2-type (immunoglobulin-like) domains. CD106 antigen is present on activated endothelial cells, tissue macrophages, dendritic cells and bone marrow fibroblasts. It is involved in the adhesion of lymphocytes, monocytes and eosinophils to activated endothelium. Recent studies shown that CD106 identifies a unique subpopulation of Mesenchymal Stem Cells (MSCs) with powerful immunosuppressive activity.

HUT78 Cell line.

Clone: 1G11 (IgG1 Mouse) The 1G11 antibody inhibits T lymphocyte adhesion to TNF-stimulated endothelial cells.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE

A66085

100 tests

Liquid

RUO

IOTest

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 82 Outside US Flow Cytometry Catalog