2020 Outside US Flow Cytometry Catalog
Single-Color Conjugated Antibodies
CD99
CD99 is an heavily O-glycosylated 32-kDa type I transmembrane protein. Its expression has been reported in many cell types, such as hematopoietic cells, endothelial cells, central nervous system ependymal cells, thymocytes, granular cells of the ovary, Sertoli cells, and pancreatic islet cells. It is variably expressed on blood cells: at high density on T cells, NK cells and erythrocytes, at low density on B cells, eosinophils and platelets. Within the functions of CD99 in cells highly expressing this antigen, studies have shown cell death of thymocytes and T lymphocytes, migration through monocyte endothelial junctions by adhesion and diapedesis, cell-cell adhesion in lymphocytes. CD99 has intercellular protein phosphorylation activity, which triggers modulation of T-cell adhesion, induction of homotypic adhesion of corticothymocytes, apoptosis and rosette formation with erythrocytes.
Lysed normal whole blood sample.
Clone: HCD99 (IgG2a Mouse)
Form
Format
Part#
Status
Line
Quality Standard
Size
ECD APC
B76291 B76270
0.5 mL 0.5 mL
Liquid Liquid
ASR ASR
IOTest IOTest
cGMP cGMP
CD103
The CD103 antigen was originally described as the human mucosal antigen 1 (HML-1) and was subsequently proved to be the integrin α E subunit. CD103 is composed of a 150 kDa chain associated with a 25 kDa chain by a disulfide bond. It is expressed as a heterodimer in association with the integrin β 7 chain. CD103 is expressed on mucosa- associated T lymphocytes and activated cells. This human intra-epithelial lymphocyte marker is expressed in very few resting peripheral blood lymphocytes. α E β 7 binds to E-cadherin on epithelial cells. Activation and TGF β -1 induce CD103 expression.
MOLT16 Cell line.
Clone: 2G5 (IgG2a Mouse) The 2G5 antibody stains a few bone marrow cells and, rarely, peripheral blood lymphocytes. 2G5 cross reacts with: Indian Rhesus, Sooty Mangabey.
Form
Format
Part#
Status
Line
Quality Standard
Size
FITC FITC APC
B49222 IM1856U B06204 IM0318
100 tests
Liquid Liquid Liquid
CE/IVD
IOTest IOTest IOTest
98/79/EC
2 mL
ASR ASR RUO
cGMP cGMP cGMP
0.5 mL 0.2 mg
UNLB
Freeze-dried
-
If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 81 Outside US Flow Cytometry Catalog
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