2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD79a

The CD79a molecule (MB-1, Ig α ) is part of the MB-1/B29 (CD79a/CD79b) disulfide- linked heterodimer which is non-covalently associated with membrane immunoglobulins (Igs) to build the B Cell antigen Receptor (BCR) complex. CD79a is a 40-45 kDa glycoprotein and belongs to the Ig superfamily of surface antigens. CD79a protein is specifically and strictly expressed throughout B lymphocyte differentiation. It appears early in ontogeny, probably before expression of cytoplasmic μ -chain, and is present in the cytoplasm of plasma cells.

Permeabilized normal whole blood sample.

Clone: HM47 (IgG1 Mouse) The HM47 antibodyis recommendedto be used in flow cytometryafter permeabilizationwith saponin-basedpermeabilizationreagentIntraPrep.The HM47 antibody reacts with a cytoplasmic epitope of the CD79a molecule. HM47 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Chimpanzee, Olive Baboon.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE PE

IM2221

100 tests

Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

IM2221U IM3456U B42018 B36287 A60793

2 mL 1 mL

ASR ASR ASR

cGMP cGMP cGMP

PC5

PC5.5

0.5 mL

APC APC

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

CD79b

The CD79b molecule (B29, Ig β ) is part of the CD79a / CD79b disulphide-linked heterodimer, non-covalently bound to surface immunoglobulins to form B cell receptors (BCR). The molecular weight of CD79b is about 33 to 40 kDa in reducing conditions. The CD79b molecule expression occurs early in B cells ontogeny. It is restricted to B lymphocytes, first appearing on the surface at the pre-B cell stage and remaining through all stages of B cell differentiation prior to plasma cells. CD79b plays an important role in the regulation of antigen receptor function like the CD3 subunits do with TCR function on T lymphocytes.

Lysed normal whole blood sample.

Clone: CB3-1 (IgG1 Mouse) The CB3-1antibodyreactswith the externalpart of the CD79bmoleculeand is to be used in flow cytometry.This antibodyis not suitablefor intracytoplasmic staining. For this application the use of the CD79a antibody is recommended. CB3-1 cross reacts with: Mink.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE PE

IM1612

100 tests

Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest

98/79/EC

IM1612U B21445 B96773 A87784

2 mL

ASR ASR

cGMP cGMP

PC5.5

0.5 mL 50 tests 0.5 mL

APC APC

CE/IVD

98/79/EC

ASR

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 75 Outside US Flow Cytometry Catalog