2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD35

The CD35 antigen is a polymorphic molecule. Different molecular weights: 160, 190, 220, 250 and 285 kDa were reported for the various allotypes. It is known as the complement receptor type I (CR1) with affinity for C3b, C4b and iC3b. The CD35 antigen is expressed by granulocytes (except basophils), B lymphocytes, a subset of T-cells, monocytes, some NK cells, erythrocytes macrophages cultured in vitro, glomerular podocytes and follicular dendritic cells. The CD35 antigen mediates phagocytosis by neutrophils and monocytes of complement coated particles.

Lysed normal whole blood sample.

Clone: J3D3 (IgG1 Mouse) The J3D3monoclonalantibodyinhibitsCR1-mediateddecayof cells boundto the alternativeand classicalpathwaysto C3-convertasesites. It also inhibitsC3b dependent rosette formation with lymphocytes.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC

IM1836 IM0195

100 tests

Liquid

RUO RUO

IOTest

cGMP cGMP

UNLB

0.2 mg

Freeze-dried

-

CD36

The CD36 antigen (platelet GPIV, or GPIIIb) is a generic term for a family of glycoproteins with molecular weights ranging from 78 to 88 kDa. CD36 expression occurs in different types of cells, including mammary epithelial cells, endothelial cells monocytes, macrophages, platelets, megakaryocytes and early erythroid cells. This molecule is also found on some human tumor cell lines. It is a very early marker of erythroid differentiation and mediates the adherence of platelets to thrombospondin and collagen. CD36 is a scavenger receptor that functions in high affinity tissue uptake of long chain fatty acids (FA). As a result of its multiple ligands and signal transduction capabilities, CD36 has also a number of functions related to immune responses, inflammation and blood disorders.

Lysed normal whole blood sample.

Clone: FA6.152 (IgG1 Mouse) The FA6-152monoclonalantibody,raisedagainstfetal erythrocytes,recognizesthe CD36familyof antigenson plateletsand certainhematopoietic ells.It does not react with lymphocytes or granulocytes. It reacts with both fetal and adult monocytes, megakaryocytes, platelets, and with reticulocytes.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB

B43302 B49201 IM0766U A87786 B46022

0.5 mL

Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest

cGMP

FITC FITC APC

100 tests

CE/IVD

98/79/EC

2 mL

ASR ASR ASR RUO

cGMP cGMP cGMP cGMP

0.5 mL 0.5 mL 0.2 mg

APC-A700

UNLB

IM0765

Freeze-dried

-

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 56 Outside US Flow Cytometry Catalog