2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD34

The CD34 antigen is a monomeric transmembrane phosphoglycoprotein of about 110 kDa with two distinct extracellular domains. The membrane proximal domain, of about 110 amino acids, probably adopts a globular conformation. The NH2-terminal domain, of about 140 amino acids, is heavily glycosylated with both N-linked glycans and sialylated O-linked carbohydrates and probably exhibits an extended rod-like structure typical of mucin-like glycoproteins. The CD34 antigen is expressed on hematopoietic progenitor cells of all lineages as well as the most primitive pluripotential stem cells. CD34 antigen expression is highest on the most primitive stem cells and is gradually lost as lineage committed progenitors differentiate. The CD34 antigen is also present on capillary endothelial cells and on bone marrow stromal cells. Variations of glycosylation are thought to occur during normal hematopoiesis depending on lineage commitment and the level of cellular maturation. Clone: Immu133 (IgG1 Mouse) Epitope Class I : Immu133 monoclonal antibody detects sialic acid-dependent class I epitope.

KG1A cell line.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE

IM1420

100 tests

Liquid

RUO

IOTest

cGMP

Clone: QBEnd10 (IgG1 Mouse) EpitopeClass II: QBEnd10reactswith early normalhematopoieticprogenitorcells, and with vascularendothelialcells. QBEnd10cross reactswith: Hamadyras Baboon.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE

IM1250U IM2650U IM0786

2 mL 1 mL

Liquid Liquid

ASR ASR RUO

IOTest IOTest

cGMP cGMP cGMP

PC5

UNLB

0.2 mg

Freeze-dried

-

Clone: 581 (IgG1 Mouse) Epitope Class III: Clone 581 recognizes a sialidase / glycoprotease / chymopapain insensitive class III epitope. 581 cross reacts with: Ovine.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC FITC

IM1870

100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

IM1870U A07776 IM1871U B49202 IM2709U A07777 IM2648U A21691 A51077 IM2472 IM2472U B92417 A86354 B92463 A89309

2 mL

ASR

cGMP

PE PE

100 tests

CE/IVD

98/79/EC

2 mL

ASR

cGMP

ECD ECD PC5 PC5 PC7 PC7 APC APC

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

APC-A700 APC-A700 APC-A750 APC-A750

50 tests 0.5 mL 50 tests 0.5 mL

CE/IVD

98/79/EC

ASR

cGMP

CE/IVD

98/79/EC

ASR

cGMP

Clone: QBEnd10 + Immu133 + Immu409 (IgG Mouse) TheCD34PoolKit includestwovials.TheonelabeledCD34Pool-PEcontainsa mixtureof QBEnd10,Immu133andImmu409.TheonelabeledIsotypicControlIgG (1+2a)-PEis its matchingnegativecontrol.As QBEnd10andImmu133are of themouseIgG1isotypeandImmu409of the IgG2aisotype,thiscontrolis a mixtureof two R-phycoerythrin-conjugatedirrelevantmousemonoclonalimmunoglobulinsof these isotypes.Each isotypeconcentrationin the controlmatchesthe total concentration of each isotype in the CD34 Pool.

Form

Format

Part#

Status

Line

Quality Standard

Size

PE

IM1459U

2 mL

Liquid

ASR

IOTest

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 55 Outside US Flow Cytometry Catalog