2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD23

The CD23 antigen (also called B6) is a transmembrane glycoprotein with a molecular weight of 45 kDa, spatially associated with the major histocompatibility complex (MHC) Class II antigen. The CD23 molecule, also named Fc ε RII is the low affinity receptor for IgE. CD23 antigen is primarily expressed on B lymphocytes and monocytes. It is also present on a large variety of other cells such as T lymphocytes, eosinophils, platelets, Langerhans cells, follicular dendritic cells (FDC), a subset of thymic epithelial cells and neutrophils. On B lymphocytes, CD23 expression is up- regulated upon activation and ultimately lost upon differentiation towards secreting- plasmocytes. A soluble form of CD23 (sCD23) exists and may be involved (like CD23) in the regulation of IgE synthesis and inflammatory phenomenom.

Lysed normal whole blood sample.

Clone: HD50 (IgG2b Mouse)

Form

Format

Part#

Status

Line

Quality Standard

Size

RD1

6604426

0.5 mL

Liquid

ASR

CYTO - STAT

cGMP

Clone: 9P25 (IgG1 Mouse) 9P25 blocks the binding of IgE. 9P25 cross reacts with: Bovine, Ovine, Equine.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB

A93689 IM0529 IM0529U B49207 A33099 IM3609U B12935 A69964 A70207

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

cGMP

FITC FITC

100 tests

CE/IVD

98/79/EC

2 mL

ASR

cGMP

PE PE

100 tests

CE/IVD

98/79/EC

2 mL 1 mL

ASR ASR ASR ASR ASR

cGMP cGMP cGMP cGMP cGMP

ECD PC7 APC

0.5 mL

1 mL

APC-A700

0.5 mL

CD24

The CD24 antigen is a glycosyl-phosphatidylinositol-linked membrane sialoglycoprotein, with a molecular weight of 35-45 kDa. CD24 is present on B cells, from the pre-B to the mature B cell stage, but not on plasma cells. It is expressed on mature granulocytes and on a variety of epithelial cell types. CD24 was discovered in mice as a heat-stable antigen and was used as a marker to differentiate hematopoietic cells and neuronal cells. It is currently known that CD24 serves as a costimulatory factor of T cells that regulate their homeostasis and proliferation, while in B cells, CD24 is functionally involved in cell activation and differentiation. In hematopoietic cells, CD24 is known to bind to molecules exhibiting danger- associated molecular patterns (DAMPs). CD24 mediates signal transduction and activates the mitogen-activated protein kinase pathway, which involves B- and T-cell development and apoptosis, cell binding and granulocyte oxidative burst.

Lysed normal whole blood sample.

Clone: ALB9 (IgG1 Mouse)

Form

Format

Part#

Status

Line

Quality Standard

Size

PE PE

B92425 IM1428U B12699 IM2645 B23133 A87785 B10738

100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

2 mL

ASR ASR ASR ASR ASR ASR RUO

cGMP cGMP cGMP cGMP cGMP cGMP cGMP

ECD PC5

0.5 mL

1 mL

PC5.5

0.5 mL 0.5 mL 0.5 mL 0.2 mg

APC

APC-A750

UNLB

IM0118

Freeze-dried

-

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 49 Outside US Flow Cytometry Catalog