2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD19

The CD19 antigen (also called B4) is a type I membrane glycoprotein with a molecular weight of 95 kDa. It is a signal transduction molecule that regulates lymphocyte development, activation, and differentiation. The molecule is expressed on all normal B lymphocytes including pro-B lymphocytes, but it is lost in maturation to plasma cells. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normal T lymphocytes, NK cells, monocytes, and granulocytes. CD19 can be associated with other surface molecules including CD21 and CD81. Co-ligation of the CD19-CD21-CD81 complex with the surface IgM-B-cell antigen receptor (BCR) leads to the phosphorylation of CD19 by Syk, followed by the recruitment of positive signal transduction effectors such as phosphatidylinositol 3 kinase (PI3 kinase), Lyn, and Fyn.

Lysed normal whole blood sample.

Clone: 89B (IgG1 Mouse)

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC FITC

6603012 6603859 6603024 6603846

100 tests 50 tests 100 tests 50 tests

Freeze-dried

IVD IVD IVD IVD

cGMP cGMP cGMP cGMP

COULTER CLONE

Liquid Liquid Liquid

CYTO - STAT

RD1 RD1

COULTER CLONE

CYTO - STAT

Clone: J3-119 (IgG1 Mouse) In vitro studiesshowthatthe CD19antibodieshavean inhibitoryeffecton the activationand proliferationof B lymphocytes.Theyalsoinhibitthe B cell response after co-stimulation by anti-immunoglobulin and interleukin 4.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB PB

B49213 A86355 A96418 A07768 IM1284U A07769 IM1285U A07770 IM2708U A07771 IM2643U B49211 A66328 IM3628 IM3628U IM2470 IM2470U B76283 B49212 A78837 A94681 A78838 IM1313

50 tests 0.5 mL 0.5 mL 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

ASR ASR

cGMP cGMP

KrO FITC FITC

CE/IVD

98/79/EC

2 mL

ASR

cGMP

PE PE

100 tests

CE/IVD

98/79/EC

2 mL

ASR

cGMP

ECD ECD PC5 PC5

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

PC5.5 PC5.5

50 tests 0.5 mL 100 tests

CE/IVD

98/79/EC

ASR

cGMP

PC7 PC7 APC APC

CE/IVD

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

1 mL

ASR ASR

cGMP cGMP

AF700

0.5 mL 50 tests 0.5 mL 50 tests 0.5 mL 0.2 mg

APC-A700 APC-A700 APC-A750 APC-A750

CE/IVD

98/79/EC

ASR

cGMP

CE/IVD

98/79/EC

ASR ASR

cGMP cGMP

UNLB

Freeze-dried

-

Clone: HD237 (IgG2b Mouse)

Form

Format

Part#

Status

Line

Quality Standard

Size

ECD

6604551

0.5 mL

Liquid

ASR

CYTO - STAT

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 46 Outside US Flow Cytometry Catalog