2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD11a

CD11a ( α L integrin, LFA-1 α chain) is a member of the integrin family. Like some other leucocyte integrins (CD11b, CD11c, CD11d), CD11a is non-covalently associated with the β 2 integrin subunit CD18. CD11a is a transmembrane glycoprotein of 170 kDa, mainly expressed by leucocytes including monocytes, macrophages, neutrophils, eosinophils, basophils, B and T lymphocytes. Activated platelets also express CD11a and CD18. LFA -1 (CD11a/CD18) promotes homotypic adhesion between lymphoid cells and heterotypic adhesion of leucocytes to the vascular endothelium. LFA-1’s known ligands are Intercellular Adhesion Molecules (ICAM): ICAM-1 (CD54), ICAM-2 (CD102) and ICAM-3 (CD50).

Lysed normal whole blood sample.

Clone: 25.3 (IgG1 Mouse) 25.3 cross reacts with: Equine, Feline, Mink.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC

IM0860U IM1433U

2 mL 2 mL

Liquid Liquid

ASR ASR

IOTest IOTest

cGMP cGMP

PE

CD11b

The CD11b antigen is also known as the integrin α M subunit. It combines with the CD18 antigen (integrin β 2 subunit) to build the integrin Mac-1 (CD11b/CD18, α M β 2, CR3, iC3bR, Mo-1). CD11b is a type I transmembrane glycoprotein of 170 or 165 kDa under reducing or non-reducing conditions, respectively. CD11b shows 19 potential N- glycosylation sites. Expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen (also known as β 2 integrin chain). Together, these two subunits create the CD11b/CD18 integrin, one of the four integrin heterodimers that can be built by the association of CD18 β chain with four distinctive CD11 α chains. CD11b/CD18 is highly expressed on NK Cells, neutrophils, monocytes and macrophages.

Lysed normal whole blood sample.

Clone: 94 (IgM Mouse) 94 cross reacts with: Indian Rhesus.

Form

Format

Part#

Status

Line

Quality Standard

Size

FITC

6602573

0.5 mg

Freeze-dried

ASR

cGMP

COULTER CLONE

Clone: Bear1 (IgG1 Mouse) Bear1 is a non blocking monoclonal antibody. Bear1 cross reacts with: Ovine, Equine, Canine.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB PB

B36296 B16891 IM0530 IM0530U IM2581U IM3611 A54822 A87782 B36295 A97052 IM0190

50 tests 0.5 mL 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

ASR

cGMP

FITC FITC

CE/IVD

98/79/EC

2 mL 2 mL 1 mL 1 mL

ASR ASR ASR ASR ASR

cGMP cGMP cGMP cGMP cGMP

PE

PC5 PC7 APC

0.5 mL 50 tests 0.5 mL 0.2 mg

APC-A750 APC-A750

CE/IVD

98/79/EC

ASR ASR

cGMP cGMP

UNLB

Freeze-dried

-

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 39 Outside US Flow Cytometry Catalog