2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD8

The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8 α homodimer or as a CD8 α / β heterodimer. CD8 α is required for surface expression of CD8 β . The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain ( α 3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8 α homodimer is expressed by NK cells and γ / δ + T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes.

Lysed normal whole blood sample.

Form Clone: B9.11 (IgG1 Mouse) The B9.11 monoclonal antibody recognizes the α chain of the CD8 molecule. It was used as a CD8 reference monoclonal antibody during HLDA 6 (ref. 6T-CD8.5). Part# Format Size Status Line Quality Standard PB IOTest CE/IVD B49182 Liquid 50 tests 98/79/EC PB IOTest ASR A82791 Liquid 0.5 mL cGMP KrO IOTest ASR B00067 Liquid 0.5 mL cGMP FITC IOTest CE/IVD A07756 Liquid 100 tests 98/79/EC FITC IOTest ASR IM0451U Liquid 2 mL cGMP PE IOTest CE/IVD A07757 Liquid 100 tests 98/79/EC PE IOTest ASR IM0452U Liquid 2 mL cGMP ECD IOTest ASR B08467 Liquid 0.5 mL cGMP PC5 IOTest CE/IVD A07758 Liquid 100 tests 98/79/EC PC5 IOTest ASR IM2638U Liquid 1 mL cGMP PC5.5 IOTest ASR B21205 Liquid 0.5 mL cGMP APC IOTest CE/IVD IM2469 Liquid 100 tests 98/79/EC APC IOTest ASR IM2469U Liquid 1 mL cGMP AF700 IOTest ASR B76279 Liquid 0.5 mL cGMP APC-A700 IOTest CE/IVD B49181 Liquid 50 tests 98/79/EC APC-A700 IOTest ASR A66332 Liquid 0.5 mL cGMP APC-A750 IOTest CE/IVD A94683 Liquid 50 tests 98/79/EC APC-A750 IOTest ASR A94686 Liquid 0.5 mL cGMP Clone: SFCI21Thy2D3 (IgG1 Mouse) SFCI21Thy2D3 monoclonal antibody recognizes the α chain of the CD8 molecule. SFCI21Thy2D3 cross reacts with: Common Marmoset. Part# Format Size Status Line Quality Standard Form

FITC FITC RD1 RD1 ECD ECD PC5 PC7 PC7 APC PC5.5

6602385 6603861 6603274 6603848 6604728 6607011 A99019 6607102 737661 A99023 737659

100 tests 50 tests 100 tests 50 tests 50 tests

Freeze-dried

IVD IVD IVD IVD

cGMP cGMP cGMP cGMP cGMP cGMP cGMP cGMP

COULTER CLONE

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CYTO - STAT

COULTER CLONE

CYTO - STAT CYTO - STAT CYTO - STAT CYTO - STAT

CE/IVD

98/79/EC

0.5 mL 0.5 mL 0.5 mL

ASR ASR ASR RUO

IOTest IOTest IOTest IOTest

100 tests 100 tests

CE/IVD

98/79/EC

0.5 mL

ASR

cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 36 Outside US Flow Cytometry Catalog