2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD5

CD5 is a type I transmembrane glycoprotein with a molecular weight of 67 kDa. The extracellular domain consists of 3 scavenger receptor cysteine-rich (SRCR) domains of nearly 100 amino acids each. The CD5 is expressed at the surface of mature T lymphocytes, by most of thymocytes and by a subpopulation of B lymphocytes (B -1a) expanded in neonatal life, several autoimmune disorders and some B-cell proliferative disorders (B-CLL). It is not found on granulocytes, monocytes and platelets. The CD5 antigen is the ligand for the B-lymphocytes cell-surface protein CD72. The CD5 / CD72 interactions are involved in the regulation of T and B lymphocyte activation and proliferation. B lymphocytes can be divided into B-1 lymphocytes and B-2 (or conventional B) lymphocytes based on different localization, functional characteristics and gene expression. The B-1 lymphocyte subset is divided into B-1a and B-1b subpopulations, which do or do not express the CD5 antigen respectively. The B-1a CD5+ B lymphocyte subset expresses immunoglobulin with inherent low affinities for self-antigens.

Lysed normal whole blood sample.

Clone: BL1a (IgG2a Mouse) BL1a monoclonal antibody (ref. 6T-CD5.5) was used as a CD5 reference monoclonal antibody during HLDA / 6. BL1a cross reacts with: Bovine, Equine.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB

A82790 A08932 IM0468U A07753 IM0469U A33096 A07754 IM2637U B49191 A70203 A21690 A51075 A60790 A78835 B92413 A78836

0.5 mL

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

ASR

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

cGMP

FITC FITC

100 tests

CE/IVD

98/79/EC

2 mL

ASR

cGMP

PE PE

100 tests

CE/IVD

98/79/EC

2 mL 1 mL

ASR ASR

cGMP cGMP

ECD PC5 PC5

100 tests

CE/IVD

98/79/EC

1 mL

ASR

cGMP

PC5.5 PC5.5

50 tests 0.5 mL 100 tests

CE/IVD

98/79/EC

ASR

cGMP

PC7 PC7 APC

CE/IVD

98/79/EC

1 mL 1 mL

ASR ASR ASR

cGMP cGMP cGMP

APC-A700 APC-A750 APC-A750

0.5 mL 50 tests 0.5 mL

CE/IVD

98/79/EC

ASR

cGMP

Clone: CLB-T1/1 (IgG1 Mouse)

Form

Format

Part#

Status

Line

Quality Standard

Size

ECD APC

B55387 B55386

0.5 mL 0.5 mL

Liquid Liquid

ASR ASR

IOTest IOTest

cGMP cGMP

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 34 Outside US Flow Cytometry Catalog