2020 Outside US Flow Cytometry Catalog

Single-Color Conjugated Antibodies

CD3

CD3 ζ see TCR ζ . The CD3 antigen is a complex of 5 invariable polypeptidic chains: γ , δ , ε , ζ and η , whose molecular weights are respectively 25-28, 21, 20, 16 and 22 kDa. The CD3 chains are clustered in a group of two invariant dimers, γ / ε and δ / ε associated with a variable dimer which consists of ζ homodimers, or ζ / η , or ζ / γ FcR heterodimers ( γ FcR being the γ chain of the Fc receptors), or γ FcR homodimers. The CD3 is part of a bigger complex which includes the T Cell Receptor (TCR). CD3 complex associated with the TCR is involved in the recognition of peptides bound to the major histocompatibility complex class I and II during the immune response. T cell activation may be induced when a foreign antigen is presented to the TCR through MHC complex. The CD3 antigen is expressed by mature T lymphocytes and by a subset of thymocytes.

Lysed normal whole blood sample.

Clone: UCHT1 (IgG1 Mouse) UCHT1reactswiththe ε -chainof the CD3complex.It wasusedas a CD3referencemAb(ref.6T-CD3.1)duringHLDA6. Afterpermeabilizationwithsaponin-based permeabilization reagent IntraPrep, it may be used to detect intracytoplasmic CD3 by flow cytometry.

Form

Format

Part#

Status

Line

Quality Standard

Size

PB PB

B49204 A93687 B00068 6604623 6604625 A07746 IM1281U A07747 IM1282U 6604621 6604627 A07748 IM2705U A07749 6607010 IM2635U B49203 A66327 6607100 737657 IM2467 IM2467U B10823 A94680 A66329 IM1280 IM1304

50 tests 0.5 mL 0.5 mL 50 tests 100 tests 100 tests

Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid Liquid

CE/IVD

IOTest IOTest IOTest

98/79/EC

ASR ASR IVD IVD

cGMP cGMP cGMP cGMP

KrO FITC FITC FITC FITC RD1 RD1 ECD ECD PC5 PC5 PC5 PE PE

CYTO - STAT

Freeze-dried

COULTER CLONE

CE/IVD

IOTest IOTest IOTest IOTest

98/79/EC

2 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

2 mL

ASR IVD IVD

cGMP cGMP cGMP

50 tests 100 tests 100 tests

CYTO - STAT

COULTER CLONE

CE/IVD

IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest IOTest

98/79/EC

1 mL

ASR

cGMP

100 tests

CE/IVD

98/79/EC

0.5 mL

ASR ASR

CYTO - STAT

cGMP cGMP

1 mL

PC5.5 PC5.5

50 tests 0.5 mL 100 tests 100 tests 100 tests 0.5 mL 50 tests 0.5 mL 1 mL

CE/IVD

98/79/EC

ASR RUO

cGMP cGMP

PC7 PC7 APC APC

CE/IVD CE/IVD

98/79/EC 98/79/EC

ASR ASR

cGMP cGMP

APC-A700 APC-A750 APC-A750

CE/IVD

98/79/EC

ASR ASR ASR

cGMP cGMP cGMP

UNLB UNLB

2 mL

- -

0.2 mg

Freeze-dried

If you require a different antibody fluorochrome combination, please refer to the Custom Design Services on page 14 or contact us via: cds.support@beckman.com ANTIBODIES & KITS 32 Outside US Flow Cytometry Catalog