2020 Outside US Flow Cytometry Catalog

DURAClone Panels

DURAClone SC

The dry DURAClone SC Mesenchymal antibody panel has been optimized for the characterization of human mesenchymal stem cells The DURAClone SC Mesenchymal tube design accommodates additional antibodies and DNA dyes in liquid format as well as fixable viability dyes to adapt to specific experimental questions and biological materials.

• Pre-formulated 8 color antibody panel • Unitized dry Beckman Coulter proprietary format • Expert-proven marker combinations • 25 tests/package • Including 3 dye lot-matched compensation kits.

Size

Status

Part #

DURAClone SC Mesenchymal

C34369

25 tests

RUO

NEW

Detection of CD73+ CD90+ CD105+/- CD34+/- mesenchymal cells. Mesenchymal Stem Cells (MSCs) are considered as potent cellular mediators of immunosuppression and tissue remodeling. Unlike other cellular interventions, MSCs can be applied in an allogeneic mode, making them a potent candidate for the development of immunosuppressive cellular products.

While MSCs show negative staining for CD45, CD31, CD14 and CD19, positive staining is observed for CD73 and CD90. Expression of CD34, CD105 and CD146 varies depending on the source materials and the stage of MSC differentiation.

Fluorochrome

Clone (Isotype)

Specificity

CD90

FITC

F15-42-1-5 (IgG1 Mouse)

CD73

AD-2 (IgG1 Mouse)

CD34

ECD

581 (IgG1 Mouse)

CD146

PC5.5

TEA 1/34 (IgG2a Mouse)

CD105

PC7

TEA3/17.1.1 (IgG1 Mouse)

CD45

APC-Alexa Fluor* 750

J33 (IgG1 Mouse)

CD31

Pacific Blue*

5.6E (IgG1 Mouse)

CD14

Krome Orange

RMO52 (IgG2a Mouse)

Stromal Vascular Fraction.

CD19

Krome Orange

J3-119 (IgG1 Mouse)

Not available in all geographies. DURAClone Panels are available for Research Use Only. Not for use in diagnostics procedures.

ANTIBODIES & KITS

181

Outside US Flow Cytometry Catalog